Ling Tian

TL;DR: It is shown that immunotherapy of tumors using fixed xenogeneic whole endothelial cells as a vaccine was effective in affording protection from tumor growth, inducing regression of established tumors and prolonging survival of tumor-bearing mice.

TL;DR: It is found that immunogene tumor therapy with a vaccine based on XVEGF was effective at both protective and therapeutic antitumor immunity in several tumor models in mice, and may provide a vaccine strategy for cancer therapy through the induction of autoimmunity against the growth factors associated with tumor growth.

TL;DR: It is found that immunotherapy with qVEGFR was effective at protective and therapeutic antitumor immunity in several solid and hematopoietic tumor models in mice, and may provide a vaccine strategy for cancer therapy through the induction of autoimmunity against the growth factor receptor associated with angiogenesis in a cross-reaction with single xenogeneic homologous protein.

TL;DR: It is shown here that vaccination with Xenopus FGFR-1 (pxFR1) is effective at antitumor immunity in three murine models, and may provide a new vaccine strategy for cancer therapy through the induction of autoimmunity against FG FR-1 associated with angiogenesis in a cross-reaction.

TL;DR: The data indicate that AdIL-12-MSC possess the potential for tropism to preclinical tumor lesions and deprives surviving or hibernating tumor cells, which have escaped from conventional treatments, of revival and recurrence.