Yang Wu

TL;DR: It is shown that immunotherapy of tumors using fixed xenogeneic whole endothelial cells as a vaccine was effective in affording protection from tumor growth, inducing regression of established tumors and prolonging survival of tumor-bearing mice.

TL;DR: A possible mechanism of CTX-induced immunopotentiation is suggested that could augment antitumor immune responses of DC vaccine by reducing the proportion of CD4+CD25+FoxP3+ Treg cells in tumor-bearing mice.

TL;DR: It is found that immunogene tumor therapy with a vaccine based on XVEGF was effective at both protective and therapeutic antitumor immunity in several tumor models in mice, and may provide a vaccine strategy for cancer therapy through the induction of autoimmunity against the growth factors associated with tumor growth.

TL;DR: It is found that immunotherapy with qVEGFR was effective at protective and therapeutic antitumor immunity in several solid and hematopoietic tumor models in mice, and may provide a vaccine strategy for cancer therapy through the induction of autoimmunity against the growth factor receptor associated with angiogenesis in a cross-reaction with single xenogeneic homologous protein.

TL;DR: It is shown that the miR-9 was underexpressed in patients with OSCC and several OSCC cell lines, and it is found that the CXC chemokine receptor 4 (CXCR4) gene was a direct target of miR,9, which led to constitutive activation of β-catenin through activation of CX CR4 expression in OSCC cells.