L
Liam O'Mahony
Researcher at University College Cork
Publications - 230
Citations - 19928
Liam O'Mahony is an academic researcher from University College Cork. The author has contributed to research in topics: Immune system & Medicine. The author has an hindex of 61, co-authored 209 publications receiving 16025 citations. Previous affiliations of Liam O'Mahony include University of Zurich & European Academy of Allergy and Clinical Immunology.
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Journal ArticleDOI
Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles
Liam O'Mahony,Jane McCarthy,Peter Kelly,George J Hurley,Fangyi Luo,Ker-Sang Chen,Gerald C. O'Sullivan,Barry Kiely,J. Kevin Collins,Fergus Shanahan,Eamonn Martin Quigley +10 more
TL;DR: B infantis 35624 alleviates symptoms in IBS; this symptomatic response was associated with normalization of the ratio of an anti-inflammatory to a proinflammatory cytokine, suggesting an immune-modulating role for this organism, in this disorder.
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In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings
Colum P. Dunne,Liam O'Mahony,Lisa Murphy,Gerardine Mary Thornton,Darrin Morrissey,Sile O'Halloran,Maria Feeney,Sarah Flynn,Gerald F. Fitzgerald,Charles Daly,Barry Kiely,Gerald C. O'Sullivan,Fergus Shanahan,John Kevin Collins +13 more
TL;DR: Criteria for in vitro selection of probiotic bacteria that may reflect certain in vivo effects on the host such as modulation of gastrointestinal tract microflora is developed.
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Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19.
Ahmet Kursat Azkur,Mübeccel Akdis,Dilek Azkur,Milena Sokolowska,Willem van de Veen,Marie-Charlotte Brüggen,Liam O'Mahony,Ya-dong Gao,Kari C. Nadeau,Cezmi A. Akdis +9 more
TL;DR: Understanding of the immune response and immunopathological changes in patients linked to deteriorating clinical conditions such as cytokine storm, acute respiratory distress syndrome, autopsy findings and changes in acute‐phase reactants, and serum biochemistry in COVID‐19 is improved.
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Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome.
Peter J. Whorwell,Linda Altringer,Jorge G. Morel,Yvonne Bond,Duane Larry Charbonneau,Liam O'Mahony,Barry Kiely,Fergus Shanahan,Eamonn Martin Quigley +8 more
TL;DR: B. infantis 35624 at a dose of 1 × 108 cfu was significantly superior to placebo and all other bifidobacterium doses for the primary efficacy variable of abdominal pain as well as the composite score and scores for bloating, bowel dysfunction, incomplete evacuation, straining, and the passage of gas at the end of the 4-wk study.
Journal ArticleDOI
Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases
Mübeccel Akdis,Simone Bürgler,Reto Crameri,Thomas Eiwegger,Hiroyuki Fujita,Enrique Gomez,Sven Klunker,Norbert Meyer,Liam O'Mahony,Oscar Palomares,Claudio Rhyner,Nadia Quaked,Anna Schaffartzik,Willem van de Veen,Sabine Zeller,Maya Zimmermann,Cezmi A. Akdis +16 more
TL;DR: In this paper, the authors review current knowledge about ILs 1 to 37 and IFN-γ and discuss their signaling pathways, cellular sources, targets, roles in immune regulation and cellular networks, role in allergy and asthma, and roles in defense against infections.