Lianbo Yu

TL;DR: In this paper, the miR-1469 was found to contribute to altered tumor cell functions mediating disease progression in primary cutaneous melanoma, which can contribute to the differences in disease progression associated with tumor ulceration.

TL;DR: This report shows that deleting a gene in pancreatic fibro Blasts causes a change in tumor-stroma co-evolution and that Ets-2 is able to act as a novel oncogene in cancer associated fibroblasts to promote pancreatic carcinogenesis.

TL;DR: Two separate mechanisms, one in G protein signalling and the other in transcriptional control, dictating PTC risk at 3q26 are demonstrated using both biochemical and genetic techniques.

TL;DR: In this article , a unique miR profile exists in ulcerated relative to nonulcerated melanoma and that miR expression inversely correlates with target genes of biologic importance.

TL;DR: This work definitively establishes the composition of the regulatory chromatin that enables HDAC1 to function as an activator and repressor at distinct target genes within the same tumor to drive transcriptional dysregulation and allow the expression of B cell specific signaling and survival networks that are critical for survival.