L
Libo Shan
Researcher at Texas A&M University
Publications - 112
Citations - 10103
Libo Shan is an academic researcher from Texas A&M University. The author has contributed to research in topics: Arabidopsis & Innate immune system. The author has an hindex of 45, co-authored 98 publications receiving 7983 citations. Previous affiliations of Libo Shan include Texas A&M Health Science Center College of Medicine & Harvard University.
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Journal ArticleDOI
Differential innate immune signalling via Ca2+ sensor protein kinases
Marie Boudsocq,Matthew R. Willmann,Matthew R. Willmann,Matthew McCormack,Horim Lee,Libo Shan,Libo Shan,Ping He,Ping He,Jenifer Bush,Shu-Hua Cheng,Jen Sheen +11 more
TL;DR: Ca2+ signalling complexity is revealed and key positive roles of specific CDPKs are demonstrated in initial MAMP signalling in plant innate immune signalling.
Journal ArticleDOI
A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity.
TL;DR: The receptor-like cytoplasmic kinase BIK1 is identified that is rapidly phosphorylated upon flagellin perception, depending on both FLS2 and BAK1, and is an essential component in MAMP signal transduction, which links the MAMP receptor complex to downstream intracellular signaling.
Journal ArticleDOI
Bacterial Effectors Target the Common Signaling Partner BAK1 to Disrupt Multiple MAMP Receptor-Signaling Complexes and Impede Plant Immunity
Libo Shan,Ping He,Jianming Li,Antje Heese,Scott C. Peck,Thorsten Nürnberger,Gregory B. Martin,Jen Sheen +7 more
TL;DR: These findings uncover a unique strategy of bacterial pathogenesis where virulence effectors block signal transmission through a key common component of multiple MAMP-receptor complexes.
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Direct Ubiquitination of Pattern Recognition Receptor FLS2 Attenuates Plant Innate Immunity
Dongping Lu,Wenwei Lin,Wenwei Lin,Xiquan Gao,Shujing Wu,Cheng Cheng,Julian Avila,Antje Heese,Timothy P. Devarenne,Ping He,Libo Shan +10 more
TL;DR: This study has revealed a unique regulatory circuit of direct ubiquitination and turnover of FLS2 by BAK1-mediated phosphorylation and recruitment of specific E3 ligases for attenuation of immune signaling.
Journal ArticleDOI
Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity.
Ping He,Libo Shan,Nai-Chun Lin,Gregory B. Martin,Birgit Kemmerling,Thorsten Nürnberger,Jen Sheen +6 more
TL;DR: A cell-based genetic screen of virulence factors and a fundamental role of MAMP signaling in nonhost immunity, and a novel action of type III effectors from pathogenic bacteria are revealed.