L
Liise Anne Pirofski
Researcher at Albert Einstein College of Medicine
Publications - 216
Citations - 12517
Liise Anne Pirofski is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Antibody & Cryptococcus neoformans. The author has an hindex of 53, co-authored 195 publications receiving 10526 citations. Previous affiliations of Liise Anne Pirofski include Montefiore Medical Center & Yeshiva University.
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Journal ArticleDOI
The convalescent sera option for containing COVID-19.
TL;DR: The efforts in design and synthesis which led to submicromolar covalent inhibitors when the enzymatic activity of the viral protease was used as a screening platform are reported.
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Deployment of convalescent plasma for the prevention and treatment of COVID-19.
Evan M. Bloch,Shmuel Shoham,Arturo Casadevall,Bruce S. Sachais,Beth H. Shaz,Jeffrey L. Winters,Camille M. van Buskirk,Brenda J. Grossman,Michael J. Joyner,Jeffrey P. Henderson,Andrew Pekosz,Bryan Lau,Amy Wesolowski,Louis M. Katz,Hua Shan,Paul G. Auwaerter,David L. Thomas,David J. Sullivan,Nigel Paneth,Eric A. Gehrie,Steven L. Spitalnik,Eldad A. Hod,Lewis Pollack,Wayne T. Nicholson,Liise Anne Pirofski,Jeffrey A. Bailey,Aaron A.R. Tobian +26 more
TL;DR: An overview of convalescent plasma is provided, from evidence of benefit, regulatory considerations, logistical work flow and proposed clinical trials, as scale up is brought underway to mobilize this critical resource.
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Host-Pathogen Interactions: Redefining the Basic Concepts of Virulence and Pathogenicity
TL;DR: Historical concepts of microbial pathogenicity and virulence are reviewed, new definitions are proposed, and a classification system for microbial pathogens based on their ability to cause damage as a function of the host’s immune response is suggested.
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The damage-response framework of microbial pathogenesis
TL;DR: A new theoretical approach to understanding microbial pathogenesis, known as the 'damage-response' framework, is proposed, which aims to address the impediment to studies of host–microorganism interactions.
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Host-pathogen interactions: basic concepts of microbial commensalism, colonization, infection, and disease.
TL;DR: The origin and historical evolution of key concepts used to describe the outcome of host-microbe interactions, namely, infection, commensalism, colonization, persistence, infection and disease, are critically reviewed.