L
Lina Ghibelli
Researcher at University of Rome Tor Vergata
Publications - 123
Citations - 8250
Lina Ghibelli is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 40, co-authored 115 publications receiving 7369 citations. Previous affiliations of Lina Ghibelli include University of Chicago.
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Pharmacological potential of cerium oxide nanoparticles
TL;DR: The biological effects of nanoceria as they emerge from in vitro and in vivo studies are reviewed, considering biocompatibility and the peculiar antioxidant mechanisms.
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Copper Nanoparticle/Polymer Composites with Antifungal and Bacteriostatic Properties
Nicola Cioffi,Luisa Torsi,Nicoletta Ditaranto,Giuseppina Tantillo,Lina Ghibelli,Luigia Sabbatini,Teresa Bleve-Zacheo,Maria D'alessio,P. Giorgio Zambonin,Enrico Traversa +9 more
TL;DR: A spinnable coating capable of releasing metal species to a broth of living organisms in a controlled manner is an extremely interesting material for a number of biotechnological applications as discussed by the authors.
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The Role of cyclooxygenase-2 in Cell Proliferation and Cell Death in Human Malignancies
TL;DR: The findings prompt us to analyze here the effects of a combination of COX-2 inhibitors together with different clinically used therapeutic strategies in order to further improve the efficiency of future anticancer treatments.
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Ce3+ Ions Determine Redox-Dependent Anti-apoptotic Effect of Cerium Oxide Nanoparticles
Ivana Celardo,Milena De Nicola,Corrado Mandoli,Jens Z. Pedersen,Enrico Traversa,Lina Ghibelli +5 more
TL;DR: Doping with increasing concentrations of Sm(3+), which progressively decreased Ce(3+) without affecting oxygen vacancies, blunted these effects, demonstrating that Ce( 3+)/Ce(4+) redox reactions are responsible for the outstanding biological properties of nanoceria.
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Rescue of cells from apoptosis by inhibition of active GSH extrusion
Lina Ghibelli,C. Fanelli,Giuseppe Rotilio,E. Lafavia,Simona Coppola,C. Colussi,Patrizia Civitareale,M.R. Ciriolo +7 more
TL;DR: Evidence indicates that extrusion of reduced glutathione precedes and is responsible for the irreversible morphofunctional changes of apoptosis, probably by altering the intracellular redox state without intervention of reactive oxygen species, thus giving a rationale for the development of redox‐dependent apoptosis under anaerobic conditions.