L
Lisa A. Racie
Researcher at Genetics Institute, Inc.
Publications - 31
Citations - 2372
Lisa A. Racie is an academic researcher from Genetics Institute, Inc.. The author has contributed to research in topics: cDNA library & Polynucleotide. The author has an hindex of 11, co-authored 31 publications receiving 2233 citations. Previous affiliations of Lisa A. Racie include Massachusetts Institute of Technology.
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Journal ArticleDOI
Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis.
Sha Mi,Xinhua Lee,Xiangping Li,Geertruida M. Veldman,Heather Finnerty,Lisa A. Racie,Edward R. Lavallie,Xiang-Yang Tang,Philippe Edouard,Steve Howes,James C. Keith,John M. Mccoy,John M. Mccoy +12 more
TL;DR: It is shown that expression of recombinant syncytin in a wide variety of cell types induces the formation of giant syncytia, and that fusion of a human trophoblastic cell line expressing endogenousSyncytin can be inhibited by an anti-syncytin antiserum, and thus may be important in human placental morphogenesis.
Patent
Secreted proteins and polynucleotides encoding them
Kenneth Jacobs,John M. Mccoy,Edward R. Lavallie,Lisa A. Racie,David Merberg,Maurice Treacy,Vikki Spaulding,Michael J. Agostino +7 more
TL;DR: In this paper, the authors provided 15 clones comprising cDNAs encoding secreted proteins, isolated from a human PBMC, from neural tissue and from a dendritic cell cDNA library.
Patent
Secreted expressed sequence tags (sests)
Kenneth Jacobs,John M. Mccoy,Edward R. Lavallie,Lisa A. Racie,David Merberg,Maurice Treacy,Vikki Spaulding,Michael J. Agostino +7 more
TL;DR: In this paper, secreted expressed sequence tags (sESTs) isolated from a variety of human tissue sources were used to identify human tissue types and organs, including human organs.
Journal ArticleDOI
Cloning and functional expression of a cDNA encoding the catalytic subunit of bovine enterokinase
Edward R. Lavallie,A Rehemtulla,Lisa A. Racie,E.A. DiBlasio,C Ferenz,Kathleen L. Grant,A Light,John M. Mccoy +7 more
TL;DR: The cloning and functional expression of a cDNA encoding the catalytic domain (light chain) of bovine enterokinase is reported and the nucleotide sequence of this cloned cDNA predicts a 235-amino acid polypeptide that shares a high degree of homology with a variety of mammalian serine proteases involved in digestion, coagulation, and fibrinolysis.
Journal ArticleDOI
Estrogen Receptor β Agonism Increases Survival in Experimentally Induced Sepsis and Ameliorates the Genomic Sepsis Signature: A Pharmacogenomic Study
Eirini Christaki,Steven M. Opal,James C. Keith,Nubar Kessinian,John E. Palardy,Nicolas A. Parejo,Edward R. Lavallie,Lisa A. Racie,William M. Mounts,Michael S. Malamas,Richard E. Mewshaw,Heather A. Harris,George P. Vlasuk +12 more
TL;DR: ERbeta agonist administration provided a survival advantage in septic animals and appears to be a promising therapeutic modality in sepsis.