L
Lisa C. Hudgins
Researcher at Cornell University
Publications - 50
Citations - 3399
Lisa C. Hudgins is an academic researcher from Cornell University. The author has contributed to research in topics: Familial hypercholesterolemia & Adipose tissue. The author has an hindex of 24, co-authored 47 publications receiving 3086 citations. Previous affiliations of Lisa C. Hudgins include The Rogosin Institute & Rockefeller University.
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Journal ArticleDOI
Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss
Paul Cohen,Makoto Miyazaki,Nicholas D. Socci,Aaron Hagge-Greenberg,Wolfgang Liedtke,Alexander A. Soukas,Ratnendra Sharma,Lisa C. Hudgins,James M. Ntambi,Jeffrey M. Friedman +9 more
TL;DR: Ob/ob mice with mutations in SCD-1 were significantly less obese than ob/ob controls and had markedly increased energy expenditure, suggesting that down-regulation of SCD1 is an important component of leptin's metabolic actions.
Journal ArticleDOI
Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet.
Lisa C. Hudgins,Marc K. Hellerstein,Christine E. Seidman,Richard A. Neese,J Diakun,Jules Hirsch +5 more
TL;DR: The dietary substitution of carbohydrate for fat stimulated fatty acid synthesis and the plasma accumulation of palmitate-enriched, linoleate-deficient triglyceride was the likely cause for the accumulation of triglyceride palMITate and "dilution" of linoleates.
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Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects
Lisa C. Hudgins,Marc K. Hellerstein,Cynthia E. Seidman,Richard A. Neese,Jolanta D. Tremaroli,Jules Hirsch +5 more
TL;DR: Eucaloric, solid food diets which are very low in fat and high in simple sugars markedly stimulate fatty acid synthesis from carbohydrate, and plasma triglycerides increase in proportion to the amount of fatty acids synthesis.
Journal ArticleDOI
Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase
Peter Weinstock,Sanja Levak-Frank,Lisa C. Hudgins,Herbert Radner,Jeffrey M. Friedman,Rudolf Zechner,Jan L. Breslow +6 more
TL;DR: Findings reveal marked alterations in AT metabolism that occur during LPL deficiency and provide strong evidence for a role of AT LPL in one type of genetic obesity.
Journal ArticleDOI
Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry.
Emil M. deGoma,Zahid Ahmad,Emily C. O'Brien,Iris Kindt,Peter Shrader,Connie B. Newman,Yashashwi Pokharel,Seth J. Baum,Linda C. Hemphill,Lisa C. Hudgins,Catherine D. Ahmed,Samuel S. Gidding,Danielle Duffy,William A. Neal,Katherine Wilemon,Matthew T. Roe,Daniel J. Rader,Christie M. Ballantyne,MacRae F. Linton,P. Barton Duell,Michael D. Shapiro,Patrick M. Moriarty,Joshua W. Knowles +22 more
TL;DR: In this article, the authors conducted a cross-sectional analysis of 1295 adults with heterozygous FH enrolled in the Cascade Screening for Awareness and Detection (CASCADE) of FH Registry to address this knowledge gap.