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Liu-Zhu Gong

Researcher at University of Science and Technology of China

Publications -  106
Citations -  4029

Liu-Zhu Gong is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 30, co-authored 103 publications receiving 3174 citations. Previous affiliations of Liu-Zhu Gong include Center for Excellence in Education & Chinese Academy of Sciences.

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A Highly Efficient Organocatalyst for Direct Aldol Reactions of Ketones with Aldedydes

TL;DR: In this paper, L-proline amides derived from various chiral beta-amino alcohols that bear substituents with various electron natures at their stereogenic centers are prepared and evaluated for catalyzing the direct Aldol reaction of 4-nitrobenzaldehyde with acetone.
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Cooperative catalysis with chiral Brønsted acid-Rh2(OAc)4: highly enantioselective three-component reactions of diazo compounds with alcohols and imines.

TL;DR: An asymmetric three-component reaction of diazo compounds and alcohols with imines catalyzed cooperatively by a rhodium complex and a chiral Brønsted acid provides a general and efficient entry to beta-amino-alpha-hydroxyl acid derivatives in high yields with excellent stereoselectivities.
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Consecutive intramolecular hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Brønsted acid binary system.

TL;DR: Consecutive hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Brønsted acid binary system has been described for the direct transformation of 2-(2-propynyl)aniline derivatives into tetrahydroquinolines with high enantiomeric purity.
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Highly Enantioselective Alkylation Reaction of Enamides by Brønsted-Acid Catalysis

TL;DR: A phosphoric acid derived from H8-BINOL enabled an asymmetric alpha-alkylation of enamides with indolyl alcohols to give beta-aryl 3-(3-indolyl)propanones in high yields and with excellent enantioselectivity.