Journal ArticleDOI
Highly Enantioselective Alkylation Reaction of Enamides by Brønsted-Acid Catalysis
TLDR
A phosphoric acid derived from H8-BINOL enabled an asymmetric alpha-alkylation of enamides with indolyl alcohols to give beta-aryl 3-(3-indolyl)propanones in high yields and with excellent enantioselectivity.About:
This article is published in Organic Letters.The article was published on 2009-09-11. It has received 188 citations till now. The article focuses on the topics: Alkylation & Phosphoric acid.read more
Citations
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Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates
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Asymmetric hydrogenation of heteroarenes and arenes.
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Asymmetric ion-pairing catalysis.
Katrien Brak,Eric N. Jacobsen +1 more
TL;DR: This review describes developments in the burgeoning field of asymmetric ion-pairing catalysis with an emphasis on the insights that have been gleaned into the structural and mechanistic features that contribute to high asymmetric induction.
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The progression of chiral anions from concepts to applications in asymmetric catalysis
TL;DR: This Review both reflects on the origins as well as details a selection of the latest examples of an area that has advanced considerably within the past five years or so: the use of chiral anions in asymmetric catalysis.
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Organocatalytic strategies for the asymmetric functionalization of indoles
TL;DR: This critical review documents the development of organocatalytic indole alkylation strategies, until the end of 2009 (127 references).
References
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Book
Catalytic Asymmetric Synthesis
TL;DR: Asymmetric Hydrogenation (T. Ohkuma, et al. as discussed by the authors ), asymmetric carbon-Carbon Bond-Forming Reactions (K. Nozaki & I. Negishi). Asymmetric Addition and Insertion Reactions of Catalytically-Generated Metal Carbenes (M. O'Donnell), and asymptotic phase-transfer Reactions.
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Small-molecule H-bond donors in asymmetric catalysis.
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Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes
TL;DR: The enantioselective intermolecular α-alkylation of aldehydes has been accomplished using an interwoven activation pathway that combines both the photoredox catalyst Ru(bpy)3Cl2 and an imidazolidinone organocatalyst.