Liwei Tan

TL;DR: In vivo antitumor studies reveal that NLG919/IR780 micelles effectively suppress the growth of tumor margin following PTT in primary tumors, and a nanosystem with the properties of photothermal conversion and regulation of the tryptophan metabolic pathway is used to suppress the tumor margin beyond effective PTT.

TL;DR: The results demonstrated Lyp-1 modification has enhanced the tumor targeting delivery of DTX and IR820, which indicated that the nanosystem constructed in this study may provide an alternative candidate for mild PTT.

TL;DR: The oral DTX-micelle-hydrogel system was effective in inhibiting tumor growth in subcutaneous 4T1 breast cancer model, and decreased systemic toxicity compared with intravenous treatment, and might be a promising candidate oral drug for breast cancer therapy.

TL;DR: Results proved that the VER-155008- micelles can attenuate the heat-resistance of tumor cells and enhance the therapeutic outcome of mild-temperature photothermal therapy.

TL;DR: A new H2O2-responsive nanomedicine for CO therapy is constructed by effectively encapsulating the hydrophobic manganese carbonyl prodrug into an advanced hollow mesoporous silica nanoparticle carrier, exhibiting high in vitro and in vivo efficacies of CO therapy.