L
Lize van der Merwe
Researcher at University of the Western Cape
Publications - 84
Citations - 2386
Lize van der Merwe is an academic researcher from University of the Western Cape. The author has contributed to research in topics: Population & Single-nucleotide polymorphism. The author has an hindex of 29, co-authored 84 publications receiving 2121 citations. Previous affiliations of Lize van der Merwe include South African Medical Research Council & Medical Research Council.
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Journal ArticleDOI
β-Lactams against Tuberculosis — New Trick for an Old Dog?
Andreas H. Diacon,Lize van der Merwe,Marinus Barnard,Florian von Groote-Bidlingmaier,Christoph Lange,Alberto L. García-Basteiro,Esperança Sevene,Lluis Ballell,David Barros-Aguirre +8 more
TL;DR: The outlook for patients with tuberculosis who do not show a response to the key agents used in treatment is grim and reminiscent of the plight of patients with cancer in the era before chemotherapy, so repurposing or combining commercially available products may offer a faster track to new antituberculosis regimens.
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Low lopinavir plasma or hair concentrations explain second-line protease inhibitor failures in a resource-limited setting.
Gert U. van Zyl,Thijs E van Mens,Helen McIlleron,Michele Zeier,Jean B. Nachega,Eric H Decloedt,Carolina Malavazzi,Pete Smith,Yong Huang,Lize van der Merwe,Monica Gandhi,Gary Maartens +11 more
TL;DR: A threshold plasma lopinavir concentration and/or hair concentration are valuable in determining the aetiology of virologic failure and identifying patients in need of adherence counselling or resistance testing.
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Neuropsychological task performance in bipolar spectrum illness: genetics, alcohol abuse, medication and childhood trauma.
TL;DR: Verbal recall deficits may be one manifestation of a genetically driven dysfunction of frontal-striatal cortical networks in BPD I.
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A prospective gait analysis study in patients with diplegic cerebral palsy 20 years after selective dorsal rhizotomy.
Nelleke G. Langerak,Robert P. Lamberts,A. Graham Fieggen,Jonathan C. Peter,Lize van der Merwe,Warwick J. Peacock,Christopher L. Vaughan +6 more
TL;DR: Twenty years after undergoing SDR, patients showed improved locomotor function compared with their preoperative status, leading to improved walking speed and temporal-distance parameters were significantly greater at 20 years than preoperative values.
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Genotype and Childhood Sexual Trauma Moderate Neurocognitive Performance: A Possible Role for Brain-Derived Neurotrophic Factor and Apolipoprotein E Variants
TL;DR: The finding of an environmental effect on memory performance and a gene-environment interaction on this hypothetical endophenotype of BPD illustrates the difficulty of identifying genetically and phenotypically simple intermediate traits for molecular genetic studies.