L
Lokendra V. Chauhan
Researcher at Columbia University
Publications - 15
Citations - 993
Lokendra V. Chauhan is an academic researcher from Columbia University. The author has contributed to research in topics: Borrelia miyamotoi & Gene. The author has an hindex of 11, co-authored 13 publications receiving 675 citations.
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Journal ArticleDOI
Identification of Rodent Homologs of Hepatitis C Virus and Pegiviruses
Amit Kapoor,Peter Simmonds,Troels K. H. Scheel,Troels K. H. Scheel,Brian Hjelle,John M. Cullen,Peter D. Burbelo,Lokendra V. Chauhan,Raja Duraisamy,Maria Sanchez Leon,Komal Jain,Kurt J. Vandegrift,Charles H. Calisher,Charles M. Rice,W. Ian Lipkin +14 more
TL;DR: These novel viruses may enable the development of small-animal models for HCV, the most common infectious cause of liver failure and hepatocellular carcinoma after hepatitis B virus, and help to explore the health relevance of the highly prevalent human pegiviruses.
Journal ArticleDOI
A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19.
Max R. O'Donnell,Beatriz Grinsztejn,Matthew J. Cummings,Jessica Justman,Matthew R. Lamb,Christina M. Eckhardt,Neena M. Philip,Ying Kuen Cheung,Vinay Gupta,Esau Joao,José Henrique Pilotto,Maria Pia Diniz,Sandra W. Cardoso,Darryl Abrams,Kartik N. Rajagopalan,Sarah Borden,Allison Wolf,Leon Claude Sidi,Alexandre Gomes Vizzoni,Valdilea G. Veloso,Zachary C. Bitan,Dawn E. Scotto,Benjamin J. Meyer,Samuel D. Jacobson,Alex Kantor,Nischay Mishra,Lokendra V. Chauhan,Elizabeth F. Stone,Flavia Dei Zotti,Francesca La Carpia,Krystalyn E. Hudson,Stephen A. Ferrara,Joseph E. Schwartz,Brie A. Stotler,Wen-Hsuan W. Lin,Sandeep N. Wontakal,Beth H. Shaz,Thomas Briese,Eldad A. Hod,Steven L. Spitalnik,Andrew Eisenberger,Walter Ian Lipkin +41 more
TL;DR: In a randomized, double-blind, controlled trial among adults hospitalized with severe and critical COVID-19 at 5 sites in New York City (USA) and Rio de Janeiro (Brazil), patients were randomized 2:1 to receive either convalescent plasma or normal control plasma as discussed by the authors.
Journal ArticleDOI
Neurologic manifestations in an infant with COVID-19.
Rachelle Dugue,Karla C. Cay-Martinez,Kiran T. Thakur,Joel A. Garcia,Lokendra V. Chauhan,Simon H. Williams,Thomas Briese,Komal Jain,Marc Foca,Danielle McBrian,Jennifer M. Bain,W. Ian Lipkin,Nischay Mishra +12 more
TL;DR: Cases were largely characterized by upper respiratory tract infection or pneumonia, fever, cough, and pharyngeal erythema among COVID-19–positive adult patients.
Posted ContentDOI
A randomized, double-blind, controlled trial of convalescent plasma in adults with severe COVID-19
Max R. O'Donnell,Beatriz Grinsztejn,Matthew J. Cummings,Jessica Justman,Matt Lamb,Christina M. Eckhardt,Neena Phillip,Kenneth Cheung,Darryl Abrams,Vinay Gupta,Maria Pia Diniz,Sandra W. Cardoso,Kartik N. Rajagopalan,Sarah Borden,Allison Wolf,Zachary C. Bitan,Benjamin J. Meyer,Samuel G. Jacobson,Alex Kantor,Nischay Mishra,Eldad A. Hod,Thomas Briese,Leon Claude Sidi,Sandeep N. Wontakal,Krystalyn E. Hudson,Brie A. Stotler,Wen-Hsuan W. Lin,José Henrique Pilotto,Esau Joao,Lokendra V. Chauhan,Valdilea G. Veloso,Joseph E. Schwartz,Elizabeth F. Stone,Flavia Dei Zotti,Francesca La Carpia,Beth H. Shaz,Stephen A. Ferrara,Alexandre Gomes Vizzoni,Steven Spitalnick,Andrew Eisenberger,W. Ian Lipin +40 more
TL;DR: In this paper, the clinical efficacy and safety of convalescent plasma among adults hospitalized with severe and critical COVID-19 was evaluated in a randomized controlled trial conducted from April 21st to November 27th, 2020.
Journal ArticleDOI
Virome Analysis of Transfusion Recipients Reveals a Novel Human Virus That Shares Genomic Features with Hepaciviruses and Pegiviruses
Amit Kapoor,Arvind Kumar,Peter Simmonds,Nishit Bhuva,Lokendra V. Chauhan,Bohyun Lee,Amadou A. Sall,Zhezhen Jin,Stephen Morse,Beth H. Shaz,Peter D. Burbelo,W. Ian Lipkin +11 more
TL;DR: Investigation of changes in the virome composition of blood transfusion recipients pre- and posttransfusion detected and genetically characterized a novel human virus that shares features with hepatitis C virus (HCV) and human pegivirus (HPgV; formerly called GB virus C or hepatitis G virus).