L
Lorenza Putignani
Researcher at Boston Children's Hospital
Publications - 204
Citations - 7964
Lorenza Putignani is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Gut flora & Medicine. The author has an hindex of 40, co-authored 167 publications receiving 5660 citations. Previous affiliations of Lorenza Putignani include Università Campus Bio-Medico & Sapienza University of Rome.
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Journal ArticleDOI
Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach
Federica Del Chierico,Valerio Nobili,Pamela Vernocchi,Alessandra Russo,Cristiano De Stefanis,Daniela Gnani,Cesare Furlanello,Alessandro Zandonà,Paola Paci,Giorgio Capuani,Bruno Dallapiccola,Alfredo Miccheli,Anna Alisi,Lorenza Putignani +13 more
TL;DR: An Oscillospira decrease coupled to a 2‐butanone up‐regulation and increases in Ruminococcus and Dorea were identified as gut microbiota signatures of NAFL onset and NAFL‐NASH progression, respectively.
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Gut Microbiota, Lipopolysaccharides, and Innate Immunity in the Pathogenesis of Obesity and Cardiovascular Risk
TL;DR: A comprehensive breakdown of the interaction among gut microbiota, LPSs, and the innate immune system in the development of obesity and promotion of an individual's cardiovascular risk is given.
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PCR-RFLP analysis of the Cryptosporidium oocyst wall protein (COWP) gene discriminates between C. wrairi and C. parvum, and between C. parvum isolates of human and animal origin
Furio Spano,Lorenza Putignani,James McLauchlin,David P. Casemore,Andrea Crisanti,Andrea Crisanti +5 more
TL;DR: The polymerase chain reaction was used to clone two distinct 550 bp-long DNA fragments of the gene encoding the Cryptosporidium oocyst wall protein (COWP) of C. wrairi, which showed 98% identity to the C. parvum homologue.
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Hepatocellular Carcinoma Is Associated With Gut Microbiota Profile and Inflammation in Nonalcoholic Fatty Liver Disease.
Francesca Romana Ponziani,Sherrie Bhoori,Chiara Castelli,Lorenza Putignani,Licia Rivoltini,Federica Del Chierico,Maurizio Sanguinetti,Daniele Morelli,Francesco Paroni Sterbini,Valentina Petito,Sofia Reddel,Riccardo Calvani,Chiara Camisaschi,Anna Picca,Alessandra Tuccitto,Antonio Gasbarrini,Maurizio Pompili,Vincenzo Mazzaferro +17 more
TL;DR: It is suggested that in patients with cirrhosis and NAFLD the gut microbiota profile and systemic inflammation are significantly correlated and can concur in the process of hepatocarcinogenesis.
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Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health
TL;DR: The use of biostatistics and mathematical approaches coupled with metabolomics play a key role in the extraction of biologically meaningful information from wide datasets as discussed by the authors, which can offer deep insights on the impact of lifestyle and dietary factors on chronic and acute diseases.