L
Licia Rivoltini
Researcher at University of Milan
Publications - 257
Citations - 22886
Licia Rivoltini is an academic researcher from University of Milan. The author has contributed to research in topics: Melanoma & Antigen. The author has an hindex of 75, co-authored 245 publications receiving 20829 citations. Previous affiliations of Licia Rivoltini include National Institutes of Health.
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Journal ArticleDOI
Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.
Yutaka Kawakami,Siona Eliyahu,Cynthia H. Delgado,Paul F. Robbins,Licia Rivoltini,Suzanne L. Topalian,Toru Miki,Steven A. Rosenberg +7 more
TL;DR: A gene encoding a melanocyte lineage-specific protein (MART-1) that is a widely shared melanoma antigen recognized by the T lymphocytes of patients with established malignancy is identified and opens possibilities for the development of immunotherapies for patients with melanoma.
Journal ArticleDOI
Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.
Yutaka Kawakami,Siona Eliyahu,Kazuyasu Sakaguchi,Paul F. Robbins,Licia Rivoltini,John R. Yannelli,Ettore Appella,Steven A. Rosenberg +7 more
TL;DR: One of the 9-mer peptides, AAGIGILTV, was most effective in sensitizing the T2 cells for TIL lysis and appears to be a very common immunogenic epitope for HLA-A2-restricted melanoma-specific TIL and may be useful for the development of immunotherapeutic strategies.
Journal ArticleDOI
High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients
Mariantonia Logozzi,Angelo De Milito,Luana Lugini,Martina Borghi,Luana Calabrò,Massimo Spada,Maurizio Perdicchio,Maria Marino,Cristina Federici,Elisabetta Iessi,Daria Brambilla,Giulietta Venturi,Francesco Lozupone,Mario Santinami,Veronica Huber,Michele Maio,Licia Rivoltini,Stefano Fais +17 more
TL;DR: The results suggest that the Exotest for detection of plasma exosomes carrying tumor-associated antigens may represent a novel tool for clinical management of cancer patients.
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Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.
Giovanna Andreola,Licia Rivoltini,Chiara Castelli,Veronica Huber,Paola Perego,Paola Deho,Paola Squarcina,Paola Accornero,Francesco Lozupone,Luana Lugini,Annarita Stringaro,Agnese Molinari,Giuseppe Arancia,Massimo Gentile,Giorgio Parmiani,Stefano Fais +15 more
TL;DR: The data provide evidence for a novel mechanism potentially operating in Fas tumor counterattack through the secretion of subcellular particles expressing functional FasL, which may form a sort of front line hindering lymphocytes and other immunocompetent cells from entering neoplastic lesions and exert their antitumor activity.
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Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine
Paola Filipazzi,Roberta Valenti,Veronica Huber,Lorenzo Pilla,Paola Canese,Manuela Iero,Chiara Castelli,Luigi Mariani,Giorgio Parmiani,Licia Rivoltini +9 more
TL;DR: CD14+HLA-DR-/lo cells exerting TGF-beta-mediated immune suppression represent a new subset of MSC potentially expandable by the administration of GM-CSF-based vaccines in metastatic melanoma patients.