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Luc Rochette

Researcher at University of Burgundy

Publications -  349
Citations -  10029

Luc Rochette is an academic researcher from University of Burgundy. The author has contributed to research in topics: Oxidative stress & Ischemia. The author has an hindex of 49, co-authored 326 publications receiving 8672 citations. Previous affiliations of Luc Rochette include French Institute of Health and Medical Research & University of Strathclyde.

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Diabetes, oxidative stress and therapeutic strategies

TL;DR: It appears important to develop new compounds that target key vascular ROS producing enzymes and mimic endogenous antioxidants, which might prove clinically relevant in preventing the development and/or retarding the progression of diabetes associated with vascular diseases.
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Nitric oxide synthase inhibition and oxidative stress in cardiovascular diseases: possible therapeutic targets?

TL;DR: It appears that both a lack and excess of NO production in diseases can have various important pathological implications, and NOS modulators (exogenous and endogenous) and their therapeutic effects are discussed.
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Regenerative Capacity of Adipose Derived Stem Cells (ADSCs), Comparison with Mesenchymal Stem Cells (MSCs).

TL;DR: This review analyzed the therapeutic advancement of ADSCs in comparison to bone marrow (BM) and umbilical cord (UC)-mesenchymal stem cells (MSCs) and designed the specific requirements to their best clinical practices and safety.
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Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential

TL;DR: Dietary supplementation with α-lipoic acid has been successfully employed in a variety of in vivo models of disease associated with an imbalance of redox status: diabetes and cardiovascular diseases.
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Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing.

TL;DR: ADSCs fulfill the general accepted criteria for cell-based therapies, but still need further investigations into their efficiency, taking into consideration the host-environment and patient-associated factors.