L
Luca Vanella
Researcher at University of Catania
Publications - 152
Citations - 4782
Luca Vanella is an academic researcher from University of Catania. The author has contributed to research in topics: Heme oxygenase & Adiponectin. The author has an hindex of 38, co-authored 137 publications receiving 4058 citations. Previous affiliations of Luca Vanella include University of Brescia & New York Medical College.
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Journal ArticleDOI
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats.
Angelique Nicolai,Ming Li,Dong Hyun Kim,Stephen J. Peterson,Luca Vanella,Vincenzo Positano,Amalia Gastaldelli,Rita Rezzani,Luigi Fabrizio Rodella,George S. Drummond,Claudia Kusmic,Antonio L'Abbate,Attallah Kappas,Nader G. Abraham +13 more
TL;DR: It is demonstrated that HO-1 induction improves insulin sensitivity, downregulates the peripheral endocannabinoid system, reduces adipose tissue volume, and causes adipose tissues remodeling in a model of obesity-induced insulin resistance.
Journal ArticleDOI
Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice.
Komal Sodhi,Kazuyoshi Inoue,Katherine H. Gotlinger,Martina Canestraro,Luca Vanella,Dong Hyun Kim,Vijay L. Manthati,Sreenivasulu Reddy Koduru,John R. Falck,Michal L. Schwartzman,Nader G. Abraham +10 more
TL;DR: The decrease in cyp2c expression and EETs levels in HO-2-null mice underscores the importance of the HO system in the regulation of epoxygenase levels and suggests that protection against obesity-induced cardiovascular complications requires interplay between these two systems.
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HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage.
Luca Vanella,Dong Hyun Kim,David Asprinio,Stephen J. Peterson,Ignazio Barbagallo,Angelo Vanella,Dove Goldstein,Susumu Ikehara,Attallah Kappas,Nader G. Abraham,Nader G. Abraham +10 more
TL;DR: Targeting HO-1 expression is a portal to increased osteoblast stem cell differentiation and to the attenuation of osteoporosis by the promotion of bone formation.
Journal ArticleDOI
Adipocyte Heme Oxygenase-1 Induction Attenuates Metabolic Syndrome in Both Male and Female Obese Mice
Angela Burgess,Ming Li,Luca Vanella,Dong Hyun Kim,Rita Rezzani,Luigi Fabrizio Rodella,Komal Sodhi,Martina Canestraro,Pavel Martásek,Stephen J. Peterson,Attallah Kappas,Nader G. Abraham +11 more
TL;DR: Findings offer the possibility of treating not only hypertension, but also other detrimental metabolic consequences of obesity including insulin resistance and dyslipidemia in obese populations by induction of HO-1 in adipocytes.
Journal ArticleDOI
Antiproliferative effect of oleuropein in prostate cell lines
Rosaria Acquaviva,Claudia Di Giacomo,Valeria Sorrenti,Fabio Galvano,Rosa Santangelo,Venera Cardile,Silvia Gangia,Nicolantonio D'Orazio,Nader G. Abraham,Luca Vanella +9 more
TL;DR: The results confirm the beneficial properties of olive oil and oleuropein, suggesting its possible use as an adjuvant agent in the treatment of prostatitis, in order to prevent the transformation of hypertrophic to cancerous cells.