L
Luchun Wang
Researcher at Birkbeck, University of London
Publications - 30
Citations - 1454
Luchun Wang is an academic researcher from Birkbeck, University of London. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 11, co-authored 21 publications receiving 1311 citations. Previous affiliations of Luchun Wang include University College London & University of Sheffield.
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Journal ArticleDOI
Atomic structure and hierarchical assembly of a cross-β amyloid fibril
Anthony W. P. Fitzpatrick,Galia T. Debelouchina,Marvin J. Bayro,Daniel K. Clare,Marc A. Caporini,Vikram S. Bajaj,Christopher P. Jaroniec,Luchun Wang,Vladimir Ladizhansky,Shirley A. Müller,Cait E. MacPhee,Christopher A. Waudby,Christopher A. Waudby,Helen R. Mott,Alfonso De Simone,Alfonso De Simone,Tuomas P. J. Knowles,Helen R. Saibil,Michele Vendruscolo,Elena V. Orlova,Robert G. Griffin,Christopher M. Dobson +21 more
TL;DR: Atomic-resolution structures of three amyloid polymorphs formed by an 11-residue peptide reveal the details of the packing interactions by which the constituent β-strands are assembled hierarchically into protofilaments, filaments, and mature fibrils.
Journal ArticleDOI
Structure of a type IV secretion system core complex.
Rémi Fronzes,Eva Schäfer,Eva Schäfer,Luchun Wang,Luchun Wang,Helen R. Saibil,Helen R. Saibil,Elena V. Orlova,Elena V. Orlova,Gabriel Waksman,Gabriel Waksman +10 more
TL;DR: Overall, the T4SS core complex structure is different in both architecture and composition from the other known double membrane–spanning secretion system that has been structurally characterized.
Journal ArticleDOI
Dodecameric Structure of the Small Heat Shock Protein Acr1 from Mycobacterium tuberculosis
C K Kennaway,Justin L. P. Benesch,Ulrich Gohlke,Luchun Wang,Carol V. Robinson,Elena V. Orlova,Helen R. Saibi,Nicholas H. Keep +7 more
TL;DR: In this article, the atomic structure of a related alpha-crystallin domain dimer was docked into the density to build a molecular structure of the dodecameric Acr1 complex.
Journal ArticleDOI
Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. VOLUME 280 (2005) PAGES 33419-33425
C K Kennaway,Justin L. P. Benesch,Ulrich Gohlke,Luchun Wang,Carol V. Robinson,Elena V. Orlova,Helen R. Saibil,Nicholas H. Keep +7 more
TL;DR: In this article, the atomic structure of a related α-crystallin domain dimer was docked into the density to build a molecular structure of the dodecameric Acr1 complex.
Journal ArticleDOI
Multiple Distinct Assemblies Reveal Conformational Flexibility in the Small Heat Shock Protein Hsp26
Helen E. White,Elena V. Orlova,Shaoxia Chen,Luchun Wang,Athanasios Ignatiou,Brent E. Gowen,Thusnelda Stromer,Titus M. Franzmann,Martin Haslbeck,Johannes Buchner,Helen R. Saibil +10 more
TL;DR: Cryo-electron microscopy of yeast Hsp26 reveals two distinct forms, each comprising 24 subunits arranged in a porous shell with tetrahedral symmetry, providing the flexibility required for formation of supercomplexes with non-native proteins.