Luiza Antunes de Castro-Jorge

TL;DR: Dengue viruses were shown to cause cardiac disease with clinical manifestations ranging from mild elevation of biomarkers to myocarditis and/or pericarditis, and two patients died secondary to cardiogenic shock before imaging studies.

TL;DR: This novel virus is a potential arbovirus because it replicated in arthropod and mammalian cells and therefore may be present in tick saliva and it is important to determine whether and by what means this potential virus is transmissible and to monitor the virus as a potential emerging tick-borne zoonotic pathogen.

TL;DR: It is found that MAYV can replicate in bone marrow-derived macrophages and robustly induce expression of inflammasome proteins, such as NLRP3, ASC, AIM2, and Caspase-1 (CASP1), and it is determined that MayV triggers NLRP2 inflammaome activation by inducing reactive oxygen species (ROS) and potassium efflux.

TL;DR: Investigation of NS1 is an important tool for the diagnosis of acute dengue infection, particularly in highly endemic areas, allowing for rapid treatment of patients and reduction of disease burden.

TL;DR: The results provide information about the most frequent amino acid changes and diversity of the E protein of DENV-3 and internal groups that are called lineages and sub-lineages.