Daniel Macedo de Melo Jorge

TL;DR: This work has used molecular modeling, density functional theory with correlation, virtual screening, flexible docking, molecular dynamics, ADMET predictions, and molecular interaction field studies in order to design new molecules with potential higher selectivity and enzymatic inhibitory activity over MAO-B.

TL;DR: The results provide information about the most frequent amino acid changes and diversity of the E protein of DENV-3 and internal groups that are called lineages and sub-lineages.

TL;DR: In 28 blood donations in Brazil that were deferred because of postdonation information, influenza A(H3N2) virus RNA in 1 donation was identified using metagenomic analysis, implying theoretical risk for viremia and transfusion transmission.

TL;DR: The results suggest that T. cruzi contains several GPCR-like proteins and that one of these GPCRs may be a PAF receptor, which is the main characteristic of the G protein-coupled receptors (GPCRs), including the PAF receptors.

TL;DR: The high level of B subtype in this Brazilian population reinforces the nature of the HIV epidemic in Brazil, and corroborates previous data obtained in the Brazilian HIV-infected population.