L
Lutz Trahms
Researcher at German National Metrology Institute
Publications - 313
Citations - 8576
Lutz Trahms is an academic researcher from German National Metrology Institute. The author has contributed to research in topics: Magnetic nanoparticles & Magnetic field. The author has an hindex of 48, co-authored 313 publications receiving 7736 citations. Previous affiliations of Lutz Trahms include University of Greifswald & Schering AG.
Papers
More filters
Journal ArticleDOI
Targeted delivery of magnetic aerosol droplets to the lung
Petra Dames,Petra Dames,Bernhard Gleich,Andreas W. Flemmer,Kerstin Hajek,Nicole Seidl,Frank Wiekhorst,Dietmar Eberbeck,Iris Bittmann,Christian Bergemann,Thomas Weyh,Lutz Trahms,Joseph Rosenecker,Carsten Rudolph,Carsten Rudolph +14 more
TL;DR: It is shown theoretically by computer-aided simulation, and for the first time experimentally in mice, that targeted aerosol delivery to the lung can be achieved with aerosol droplets comprising superparamagnetic iron oxide nanoparticles—so-called nanomagnetosols—in combination with a target-directed magnetic gradient field.
Journal ArticleDOI
Magnetoencephalography with a chip-scale atomic magnetometer
TL;DR: The measurement of somatosensory-evoked and spontaneous magnetoencephalography (MEG) signals with a chip-scale atomic magnetometer (CSAM) based on optical spectroscopy of alkali atoms and higher noise levels were partly compensated by higher signal amplitudes due to the shorter distance between CSAM and scalp.
Journal ArticleDOI
MEG/EEG sources of the 170-ms response to faces are co-localized in the fusiform gyrus.
I. Deffke,Tilmann Sander,J. O. Heidenreich,Werner Sommer,Gabriel Curio,Lutz Trahms,Andreas Lueschow +6 more
TL;DR: The current study aimed to specify the relation of the dipolar sources underlying N170 and M170, an important computational step in face processing, which was measured simultaneously during the presentation of unfamiliar faces.
Journal ArticleDOI
Drug loaded magnetic nanoparticles for cancer therapy
TL;DR: In an experimental cancer model, targeted drug delivery is performed and magnetic iron oxide nanoparticles are used, bound to a chemotherapeutic agent, which were attracted to an experimental tumour in rabbits by an external magnetic field (magnetic drug targeting).
Journal ArticleDOI
Efficient drug-delivery using magnetic nanoparticles--biodistribution and therapeutic effects in tumour bearing rabbits
Rainer Tietze,Stefan Lyer,Stephan Dürr,Tobias Struffert,Tobias Engelhorn,Marc Schwarz,Elisabeth Eckert,Thomas Göen,S. Vasylyev,Wolfgang Peukert,Frank Wiekhorst,Lutz Trahms,Arnd Dörfler,Christoph Alexiou +13 more
TL;DR: The importance of intra-arterial administration of drug carrying nanoparticles for magnetic drug targeting is demonstrated resulting in improved clinical outcomes in the studied animal model compared with intra-venous, confirming former pilot experiments and implying a milestone towards clinical studies.