T
Tobias Engelhorn
Researcher at University of Erlangen-Nuremberg
Publications - 179
Citations - 5027
Tobias Engelhorn is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Stroke & Magnetic resonance imaging. The author has an hindex of 36, co-authored 169 publications receiving 4224 citations. Previous affiliations of Tobias Engelhorn include Stanford University.
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Journal ArticleDOI
DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4·5 h of symptom onset (PRE-FLAIR): a multicentre observational study
Götz Thomalla,Bastian Cheng,Martin Ebinger,Qing Hao,Thomas Tourdias,Ona Wu,Jong S. Kim,Lorenz Breuer,Oliver C. Singer,Steven Warach,Soren Christensen,András Treszl,Nils D. Forkert,Ivana Galinovic,Michael Rosenkranz,Tobias Engelhorn,Martin Köhrmann,Matthias Endres,Dong-Wha Kang,Vincent Dousset,A. Gregory Sorensen,David S Liebeskind,Jochen B. Fiebach,Jens Fiehler,Christian Gerloff +24 more
TL;DR: In this article, a mismatch in visibility of acute ischaemic lesion between diffusion-weighted MRI (DWI) and fluid-attenuated inversion recovery (FLAIR) MRI was used to detect patients within the recommended time window for thrombolysis.
Journal ArticleDOI
Efficient drug-delivery using magnetic nanoparticles--biodistribution and therapeutic effects in tumour bearing rabbits
Rainer Tietze,Stefan Lyer,Stephan Dürr,Tobias Struffert,Tobias Engelhorn,Marc Schwarz,Elisabeth Eckert,Thomas Göen,S. Vasylyev,Wolfgang Peukert,Frank Wiekhorst,Lutz Trahms,Arnd Dörfler,Christoph Alexiou +13 more
TL;DR: The importance of intra-arterial administration of drug carrying nanoparticles for magnetic drug targeting is demonstrated resulting in improved clinical outcomes in the studied animal model compared with intra-venous, confirming former pilot experiments and implying a milestone towards clinical studies.
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Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema.
Nicolai E. Savaskan,Nicolai E. Savaskan,Alexandra Heckel,Eric Hahnen,Eric Hahnen,Tobias Engelhorn,Arnd Doerfler,Oliver Ganslandt,Christopher Nimsky,Michael Buchfelder,Ilker Y. Eyüpoglu +10 more
TL;DR: Results show a crucial role for xCT in glioma-induced neurodegeneration and brain edema, corroborating the concept that edema formation may be in part a consequence of peritumoral cell death.
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Flat Detector CT in the Evaluation of Brain Parenchyma, Intracranial Vasculature, and Cerebral Blood Volume: A Pilot Study in Patients with Acute Symptoms of Cerebral Ischemia
Tobias Struffert,Yu Deuerling-Zheng,Stephan P. Kloska,Tobias Engelhorn,Charles M. Strother,Willi A. Kalender,Martin Köhrmann,Siegfried A. Schwab,A. Doerfler +8 more
TL;DR: Both imaging of the cerebral vasculature and measurements of CBV by using FD-CT are feasible and the resulting vascular images and CBV measurements compared well with ones made by using standard CT techniques.
Journal Article
Surgically induced intracranial contrast enhancement: potential source of diagnostic error in intraoperative MR imaging.
Michael Knauth,Nurdagül Aras,Christian Rainer Wirtz,Arnd Dörfler,Tobias Engelhorn,Klaus Sartor +5 more
TL;DR: Careful analysis of the location, configuration, and time course of intraoperatively observed intracranial enhancement is critical to avoid confusing surgically induced contrast enhancement with contrast-enhancing, residual tumor.