M
M. Alaraby Salem
Researcher at University of Hertfordshire
Publications - 12
Citations - 224
M. Alaraby Salem is an academic researcher from University of Hertfordshire. The author has contributed to research in topics: Ocimum & Docking (molecular). The author has an hindex of 6, co-authored 12 publications receiving 114 citations.
Papers
More filters
Journal ArticleDOI
New pyrazole derivatives: Synthesis, anti-inflammatory activity, cycloxygenase inhibition assay and evaluation of mPGES
Ghaneya S. Hassan,Doaa E. Abdel Rahman,Esraa A. Abdelmajeed,Rana H. Refaey,M. Alaraby Salem,Yassin M. Nissan +5 more
TL;DR: New pyrazole derivatives 2-5 showed good inhibitory activity at a nanomolar level and most compounds exhibited selectivity towards COX-2 inhibition, while all the tested compounds exhibited potent inhibitory effect on the production of PGE2, in addition to their inhibition of COx-2 enzyme.
Journal ArticleDOI
Anti-Alzheimer potential, metabolomic profiling and molecular docking of green synthesized silver nanoparticles of Lampranthus coccineus and Malephora lutea aqueous extracts.
Khayrya A. Youssif,Eman G. Haggag,Ali M. El-Shamy,Mohamed A Rabeh,Nagwan M. Gabr,Amany Seleem,M. Alaraby Salem,Ahmed Saber Hussein,Markus Krischke,Martin J. Mueller,Usama Ramadan Abdelmohsen +10 more
TL;DR: Overall, the green synthesis of silver nanoparticles using plant extracts highlighted its promising potential in terms of anticholinesterase and antioxidant activity as plant-based anti-Alzheimer drug and against oxidative stress.
Journal ArticleDOI
New oxadiazoles with selective-COX-2 and EGFR dual inhibitory activity: Design, synthesis, cytotoxicity evaluation and in silico studies.
TL;DR: Results indicated that compound IX has a potential to serve as a lead compound for developing novel anticancer therapeutic agents.
Journal ArticleDOI
Antiulcer potential and molecular docking of flavonoids from Ocimum forskolei Benth., family Lamiaceae.
Eman Maher Zahran,Usama Ramadan Abdelmohsen,A Samir Hussein,M. Alaraby Salem,Hany Ezzat Khalil,Samar Yehia Desoukey,Mostafa A. Fouad,Mohamed Kamel +7 more
TL;DR: Results revealed that salvitin followed by sideritiflavone were the main active ones acting against M3 and H-2 receptors, respectively, and the formation of two persistent H-bonds between salvit in and two amino acids of the active site formed in 42 and 65% of the frames, respectively.
Journal ArticleDOI
Multitarget in silico studies of Ocimum menthiifolium , family Lamiaceae against SARS-CoV-2 supported by molecular dynamics simulation.
Amgad Albohy,Eman Maher Zahran,Usama Ramadan Abdelmohsen,M. Alaraby Salem,Tarfah Al-Warhi,Mohammad M. Al-Sanea,Narek Abelyan,Hany Ezzat Khalil,Samar Yehia Desoukey,Mostafa A. Fouad,Mohamed Kamel +10 more
TL;DR: Light is shed on the structure-based design of natural flavonoids as anti-SARS-CoV-2 drugs targeting the nsp16/10 complex and the high stability of acaciin-nsp16 complex with binding energy of −110 kJ/mol is suggested.