M. Coletta

TL;DR: Transplantation of genetically marked bone marrow into immunodeficient mice revealed that marrow-derived cells migrate into areas of induced muscle degeneration, undergo myogenic differentiation, and participate in the regeneration of the damaged fibers.

TL;DR: The isolation of undifferentiated cells that grow as self-adherent clusters (that are termed “cardiospheres”) from subcultures of postnatal atrial or ventricular human biopsy specimens and from murine hearts are described.

TL;DR: It is shown that acutely isolated and clonally derived neural stem cells from mice and humans could produce skeletal myotubes in vitro and in vivo, the latter following transplantation into adult animals and a community effect between neural cells may override such myogenic induction.

TL;DR: It is shown that clonable skeletal myogenic cells are present in the embryonic dorsal aorta of mouse embryos and this finding is based on a detailed clonal analysis of different tissue anlagen at various developmental stages, raising the possibility that a subset of satellite cells may derive from the vascular system.

TL;DR: It is reported that endothelial cells, either freshly isolated from embryonic vessels or established as homogenous cells in culture, differentiate into beating cardiomyocytes and express cardiac markers when cocultured with neonatal rat cardiomeocytes or when injected into postischemic adult mouse heart.