M
M. de Graaf
Researcher at Erasmus University Rotterdam
Publications - 7
Citations - 572
M. de Graaf is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Influenza A virus subtype H5N1 & H5N1 genetic structure. The author has an hindex of 6, co-authored 7 publications receiving 521 citations. Previous affiliations of M. de Graaf include University of Cambridge.
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Journal ArticleDOI
Emergence of a novel GII.17 norovirus – End of the GII.4 era?
M. de Graaf,J. van Beek,Harry Vennema,Alexander T. Podkolzin,Joanne Hewitt,Filemon Bucardo,Kate Templeton,Janet Mans,Johan Nordgren,Gábor Reuter,M. Lynch,Lasse Dam Rasmussen,Nobuhiro Iritani,Martin C.W. Chan,Vito Martella,Katia Ambert-Balay,Jan Vinjé,Peter A. White,Marion Koopmans +18 more
TL;DR: An overview of the available information on GII.P17-GII.17 norovirus in context of current knowledge on the epidemiology of noroviruses is provided to gain insight in the viral and host characteristics of this norov virus genotype.
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Predicting 'airborne' influenza viruses: (Trans-) mission impossible?
Erin M. Sorrell,Eefje J. A. Schrauwen,Martin Linster,M. de Graaf,Sander Herfst,Ron A. M. Fouchier +5 more
TL;DR: It is postulated that the minimal requirements for efficient transmission of an animal influenza virus between humans are: efficient virus attachment to (upper) respiratory tissues, replication to high titers in these tissues, and release and aerosolization of single virus particles.
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Detection of Chlamydia trachomatis in clinical specimens by the polymerase chain reaction.
H. C. J. Claas,Willem J. G. Melchers,I H de Bruijn,M. de Graaf,W. C. van Dijk,J. Lindeman,W. G. V. Quint +6 more
TL;DR: The polymerase chain reaction seems to be a sensitive and reliable method for detection of chlamydia trachomatis by the polymer enzyme chain reaction.
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Determinants of virulence of influenza A virus.
Eefje J. A. Schrauwen,M. de Graaf,Sander Herfst,Guus F. Rimmelzwaan,A.D.M.E. Osterhaus,Ron A. M. Fouchier +5 more
TL;DR: The identification and characterisation of genetic factors which could alter the virulence of influenza A viruses may provide insights into genetic traits which change virulence and help to understand which genetic determinants are of importance for the pandemic potential of animal influenza A virus.
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Transmission of influenza A/H5N1 viruses in mammals
Masaki Imai,Sander Herfst,Erin M. Sorrell,Eefje J. A. Schrauwen,Martin Linster,M. de Graaf,Ron A. M. Fouchier,Yoshihiro Kawaoka +7 more
TL;DR: A better understanding of the biological basis and genetic determinants that confer transmissibility to H5N1 influenza A viruses in mammals is important to enhance pandemic preparedness.