M
M. Elizabeth Ross
Researcher at Cornell University
Publications - 105
Citations - 9300
M. Elizabeth Ross is an academic researcher from Cornell University. The author has contributed to research in topics: Ischemia & Nitric oxide synthase. The author has an hindex of 43, co-authored 95 publications receiving 8558 citations. Previous affiliations of M. Elizabeth Ross include Harvard University & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
doublecortin, a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein
Joseph G. Gleeson,Joseph G. Gleeson,Kristina M. Allen,Jeremy W. Fox,Edward D Lamperti,Samuel F. Berkovic,Ingrid E. Scheffer,Edward C. Cooper,William B. Dobyns,Sharon R. Minnerath,M. Elizabeth Ross,Christopher A. Walsh +11 more
TL;DR: A novel 10 kb brain-specific cDNA interrupted by a balanced translocation in an XLIS patient that encodes a novel 40 kDa predicted protein named Doublecortin, which may define an Abl-dependent pathway regulating neuronal migration.
Journal ArticleDOI
Cyclo-Oxygenase-2 Gene Expression in Neurons Contributes to Ischemic Brain Damage
TL;DR: Cerebral ischemia leads to upregulation of COX-2 message, protein, and reaction products in the injured hemisphere, and the rationale for neuroprotective strategies employing COx-2 inhibitors is provided.
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Delayed Reduction of Ischemic Brain Injury and Neurological Deficits in Mice Lacking the Inducible Nitric Oxide Synthase Gene
TL;DR: Findings indicate that iNOS expression is one of the factors contributing to the expansion of the brain damage that occurs in the post-ischemic period and may provide a novel therapeutic strategy targeted specifically at the secondary progression of ischemic brain injury.
Journal ArticleDOI
G protein-coupled receptor-dependent development of human frontal cortex.
Xianhua Piao,Sean S. Hill,Adria Bodell,Bernard S. Chang,Lina Basel-Vanagaite,Rachel Straussberg,William B. Dobyns,Bassam Qasrawi,Robin M. Winter,A. Micheil Innes,Thomas Voit,M. Elizabeth Ross,Jacques L. Michaud,Jean Claude Déscarie,A. James Barkovich,Christopher A. Walsh +15 more
TL;DR: It is shown that mutations in GPR56, which encodes an orphan G protein–coupled receptor with a large extracellular domain, cause a human brain cortical malformation called bilateral frontoparietal polymicrogyria (BFPP).
Journal ArticleDOI
Reduced susceptibility to ischemic brain injury and N-methyl-d-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice
Costantino Iadecola,Kiyoshi Niwa,Shigeru Nogawa,Xueren Zhao,Masao Nagayama,Eiichi Araki,Scott G. Morham,M. Elizabeth Ross +7 more
TL;DR: It is demonstrated that COX-2-deficient mice have a significant reduction in the brain injury produced by occlusion of the middle cerebral artery, and may be a valuable therapeutic target for treatment of human stroke.