M
M. van den Berg
Researcher at Utrecht University
Publications - 104
Citations - 7460
M. van den Berg is an academic researcher from Utrecht University. The author has contributed to research in topics: Haemophilia & Aryl hydrocarbon receptor. The author has an hindex of 37, co-authored 103 publications receiving 7183 citations.
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Journal ArticleDOI
Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife
M. van den Berg,L. Birnbaum,A.T.C. Bosveld,B. Brunstrom,P. Cook,M. Feeley,John P. Giesy,Annika Hanberg,R. Hasegawa,S.W. Kennedy,T. Kubiak,J. C. Larsen,F.X.R. van Leeuwen,A. K. D. Liem,C. Nolt,R.E. Peterson,L. Poellinger,Stephen Safe,D. Schrenk,D. Tillitt,Mats Tysklind,Maged Younes,F. Waern,T. Zacharewski +23 more
TL;DR: It was concluded that the TEF concept is still the most plausible and feasible approach for risk assessment of halogenated aromatic hydrocarbons with dioxinlike properties.
Journal ArticleDOI
The toxicokinetics and metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and their relevance for toxicity.
TL;DR: Human risk assessment for PCDDs and PCDFs needs to consider species-, congener-, and dose-specific toxicokinetic data, as exposure to complex mixtures, including PCBs, has the potential to alter the toxicokinetics of individual compounds.
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2-Chloro-s-Triazine Herbicides Induce Aromatase (CYP19) Activity in H295R Human Adrenocortical Carcinoma Cells: A Novel Mechanism for Estrogenicity?
TL;DR: The observed induction of aromatase, the rate-limiting enzyme in the conversion of androgens to estrogens, may be an underlying explanation for some of the reported hormonal disrupting and tumor promoting properties of these herbicides in vivo.
Journal ArticleDOI
Hemophilia joint health score reliability study
P. Hilliard,Sharon Funk,N. Zourikian,BM Bergstrom,C. S. Bradley,M. Mclimont,Marilyn J. Manco-Johnson,Pia Petrini,M. van den Berg,Brian M. Feldman +9 more
TL;DR: This study is the first in a series to assess the psychometric properties of the HJHS, a promising new measure of joint health in boys with haemophilia.
Journal ArticleDOI
Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment.
A.P.J.M. van Birgelen,E.A. Smit,I.M. Kampen,C.N. Groeneveld,K.M. Fase,J. H. van der Kolk,H. Poiger,M. van den Berg,Jan H. Koeman,Abraham Brouwer +9 more
TL;DR: The results provide a mechanistic base for the use of certain effects on thyroid hormone metabolism by polyhalogenated aromatic compounds in risk assessment by using some other well-known Ah receptor-mediated toxic and biochemical parameters.