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M

M. von Bergwelt-Baildon

Researcher at University of Cologne

Publications -  30
Citations -  379

M. von Bergwelt-Baildon is an academic researcher from University of Cologne. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 11, co-authored 30 publications receiving 312 citations. Previous affiliations of M. von Bergwelt-Baildon include Harvard University.

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CD40-activated B cells can be generated in high number and purity in cancer patients: analysis of immunogenicity and homing potential.

TL;DR: It is shown that proliferation of B cells from cancer patients is equivalent to that observed in healthy donors, and CD40‐B cells can be expanded in virtually unlimited numbers at high purity and full function concerning antigen‐presentation and migratory properties.
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CD40 activation: potential for specific immunotherapy in B-CLL

TL;DR: Biology and potential therapeutic applications of the CD40-system in CLL are discussed and theCD40-CD40L interaction has been shown to significantly increase antigen presentation in normal and malignant B-cells.
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Rare naturally occurring immune responses to three epitopes from the widely expressed tumour antigens hTERT and CYP1B1 in multiple myeloma patients.

TL;DR: Examining whether patients with MM have an endogenous pre‐existing immune response against recently identified epitopes from hTERT and CYP1B1 suggests strategies targeting these antigens may have to utilize techniques to induce T cell responses from a naive precursor frequency.
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Linking Genomics to Immunotherapy by Reverse Immunology - ‘Immunomics’ in the New Millennium

TL;DR: This review will focus on the process from in silico analysis of expression databases and screening of potential candidate genes by bioinformatics to the in vitro and in vivo analysis to determine the immunogenicity of candidate tumor antigens.