K
KC Anderson
Researcher at Harvard University
Publications - 174
Citations - 9414
KC Anderson is an academic researcher from Harvard University. The author has contributed to research in topics: Multiple myeloma & Bortezomib. The author has an hindex of 44, co-authored 161 publications receiving 8620 citations. Previous affiliations of KC Anderson include Brigham and Women's Hospital.
Papers
More filters
Journal ArticleDOI
Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts
Elli Papaemmanuil,Mario Cazzola,Jacqueline Boultwood,Luca Malcovati,Paresh Vyas,David T. Bowen,Andrea Pellagatti,J. S. Wainscoat,Eva Hellström-Lindberg,Carlo Gambacorti-Passerini,Anna L. Godfrey,I. Rapado,Ana Cvejic,Ana Cvejic,Richard Rance,C. McGee,Peter R. Ellis,Laura Mudie,Phil Stephens,Stuart McLaren,Charles E. Massie,Patrick S. Tarpey,Ignacio Varela,Serena Nik-Zainal,Helen Davies,Adam Shlien,David T. Jones,Keiran Raine,Jonathon Hinton,Adam Butler,Jon W. Teague,E J Baxter,Joannah Score,Anna Gallì,M.G. Della Porta,Erica Travaglino,Michael J. Groves,Sudhir Tauro,Nikhil C. Munshi,Nikhil C. Munshi,KC Anderson,Adel K. El-Naggar,Andrej Fischer,Andrej Fischer,Ville Mustonen,Alan J. Warren,Nicholas C.P. Cross,Anthony R. Green,P A Futreal,Michael R. Stratton,Peter J. Campbell,Peter J. Campbell +51 more
TL;DR: Mutations in SF3B1 implicate abnormalities of messenger RNA splicing in the pathogenesis of myelodysplastic syndromes and were associated with down-regulation of key gene networks, including core mitochondrial pathways.
Journal ArticleDOI
Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative disease.
Lawrence S. Young,C Alfieri,Kevin Hennessy,H Evans,C O'Hara,KC Anderson,Jerome Ritz,R S Shapiro,Alan B. Rickinson,Elliott Kieff +9 more
TL;DR: Using monoclonal antibody-immune microscopy, it is demonstrated that these two EBV proteins and their associated B-lymphocyte activation or adhesion molecules are expressed in the infiltrating B lymphocytes in immunocompromised patients with EBV lymphoproliferative disease.
Journal ArticleDOI
Prevention of thalidomide- and lenalidomide-associated thrombosis in myeloma
Antonio Palumbo,S V Rajkumar,Meletios A. Dimopoulos,Paul G. Richardson,J F San Miguel,Bart Barlogie,J L Harousseau,Jeffrey A. Zonder,Michele Cavo,Maurizio Zangari,M. Attal,Andrew Belch,S. Knop,Douglas E. Joshua,Orhan Sezer,Heinz Ludwig,David H. Vesole,J. Bladé,Robert A. Kyle,Jan Westin,Donna M. Weber,Sara Bringhen,Ruben Niesvizky,Anders Waage,M. von Lilienfeld-Toal,Sagar Lonial,Gareth J. Morgan,Robert Z. Orlowski,Kazuyuki Shimizu,KC Anderson,Mario Boccadoro,Brian G.M. Durie,Pieter Sonneveld,Mohamad A. Hussein +33 more
TL;DR: This manuscript summarizes the available evidence and recommends a prophylaxis strategy according to a risk-assessment model for venous thromboembolism (VTE), and recommends low-molecular-weight heparin (LMWH), warfarin or aspirin.
Journal ArticleDOI
International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders
Angela Dispenzieri,Robert A. Kyle,Giampaolo Merlini,Jesús F. San Miguel,Heinz Ludwig,Roman Hájek,Antonio Palumbo,Sundar Jagannath,J. Bladé,Sagar Lonial,Meletios A. Dimopoulos,Raymond L. Comenzo,H. Einsele,Bart Barlogie,KC Anderson,Morie A. Gertz,J L Harousseau,M. Attal,Patrizia Tosi,Pieter Sonneveld,Mario Boccadoro,Gareth J. Morgan,Paul G. Richardson,O. Sezer,Maria-Victoria Mateos,Michele Cavo,Douglas E. Joshua,Ingemar Turesson,Wenming Chen,K. Shimizu,R. L. Powles,S V Rajkumar,Brian G.M. Durie +32 more
TL;DR: Consensus guidelines for the use of the serum immunoglobulin-free light chain assay are provided, in the diagnosis and management of clonal PCD.
Journal Article
IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade.
Atsushi Ogata,Dharminder Chauhan,Gerrard Teoh,Steven P. Treon,Mitsuyoshi Urashima,Robert L. Schlossman,KC Anderson +6 more
TL;DR: The data suggest that STAT1 and/or STAT3 activation may occur independently of the proliferative response to IL-6, and that activation of the MAPK cascade is an important distal pathway for IL- 6-mediated growth.