M
Madan M. Chaturvedi
Researcher at University of Delhi
Publications - 72
Citations - 9626
Madan M. Chaturvedi is an academic researcher from University of Delhi. The author has contributed to research in topics: Kinase & IκBα. The author has an hindex of 35, co-authored 71 publications receiving 8662 citations. Previous affiliations of Madan M. Chaturvedi include University of Zurich & Banaras Hindu University.
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Oxidative Stress, Inflammation, and Cancer: How Are They Linked?
TL;DR: Observations to date suggest that oxidative stress, chronic inflammation, and cancer are closely linked.
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NF-κB addiction and its role in cancer: ‘one size does not fit all’
TL;DR: Multiple mechanisms of NF-κB activation and their regulation by multitargeted agent in contrast to monotargeted agents are discussed, thus ‘one size does not fit all’ cancers.
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Role of curcumin in cancer therapy
TL;DR: Curcumin has been shown to have protective and therapeutic effects against cancers of the blood, skin, oral cavity, lung, pancreas, and intestinal tract, and to suppress angiogenesis and metastasis in rodents.
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Identification of Novel Anti-inflammatory Agents from Ayurvedic Medicine for Prevention of Chronic Diseases: “Reverse Pharmacology” and “Bedside to Bench” Approach
Bharat B. Aggarwal,Sahdeo Prasad,Simone Reuter,Ramaswamy Kannappan,Vivek R. Yadav,Byoungduck Park,Ji Hye Kim,Subash C. Gupta,Kanokkarn Phromnoi,Chitra Sundaram,Seema Prasad,Madan M. Chaturvedi,Bokyung Sung +12 more
TL;DR: Ayurveda, a science of long life, almost 6,000 years old, can serve as a "goldmine" for novel anti-inflammatory agents used for centuries to treat chronic diseases, and description of various Ayurvedic plants currently used for treatment, their active chemical components, and the inflammatory pathways that they inhibit are provided.
Journal ArticleDOI
Sanguinarine (Pseudochelerythrine) Is a Potent Inhibitor of NF-κB Activation, IκBα Phosphorylation, and Degradation
Madan M. Chaturvedi,Ashok Kumar,Bryant G. Darnay,Gagan B.N. Chainy,Sudha Agarwal,Bharat B. Aggarwal +5 more
TL;DR: It is demonstrated that sanguinarine is a potent suppressor of NF-κB activation and it acts at a step prior to IκBα phosphorylation, which suggests a critical sulfhydryl group is involved in NF-kkB activation.