Chitra Sundaram

TL;DR: Evidence that inflammation is the link between the agents/factors that cause cancer and the agents that prevent it is presented and evidence that cancer is a preventable disease that requires major lifestyle changes is provided.

TL;DR: Curcumin has been shown to exhibit antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, and anticancer activities and thus has a potential against various malignant diseases, diabetes, allergies, arthritis, Alzheimer's disease, and other chronic illnesses.

TL;DR: This review focuses on the status of all these approaches in generating a "super curcumin," a homodimer of feruloylmethane containing a methoxy group and a hydroxyl group, a heptadiene with two Michael acceptors, and an alpha,beta-diketone.

TL;DR: The activity of curcumin reported against leukemia and lymphoma, gastrointestinal cancers, genitourinary cancers, breast cancer, ovarian cancer, head and neck squamous cell carcinoma, lung cancer, melanoma, neurological cancers, and sarcoma reflects its ability to affect multiple targets.

TL;DR: Only small molecules that suppress NF-κB activation are described, and the mechanism by which they block this pathway is described.