Mads Gabrielsen

TL;DR: The yeast two-hybrid assay is used to demonstrate that MKP-1 is able to interact selectively with the extracellular signal-regulated kinase 1/2 (ERK1/2), p38α, and c-Jun NH2-terminal kinase (JNK) MAP kinase isoforms, indicating that there are distinct binding determinants for these MAP kinases.

TL;DR: Backside bound Ub (Ub(B) serves as an allosteric activator of RING E3-mediated Ub transfer, thereby improving the catalytic efficiency of Ub transfer.

TL;DR: A novel nonlinear optical method is demonstrated, angle-resolved coherent wave mixing, that separates out coherently coupled electronic transitions and energy transfers in an instantaneous two-dimensional mapping.

TL;DR: This work provides the first identification of bacterial proteins that are targeted by a class of anti-virulence compounds and provides evidence that their mode of action is likely to result from a synergistic effect arising from a perturbation of the function of several conserved proteins.

TL;DR: Cryo-electron microscopy structures of feline calicivirus and its cellular receptor show that twelve copies of the minor capsid protein VP2 form a portal-like assembly arranged about a pore in the capsid shell, hypothesized to function as a channel for the delivery of the calicvirus genome through the endosomal membrane, into the cytoplasm of a host cell, thereby initiating infection.