M
Mahendra Mariadassou
Researcher at Université Paris-Saclay
Publications - 90
Citations - 2628
Mahendra Mariadassou is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Multivariate statistics & Phylogenetic tree. The author has an hindex of 22, co-authored 84 publications receiving 1780 citations. Previous affiliations of Mahendra Mariadassou include University of Basel & Paris Descartes University.
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Journal ArticleDOI
FROGS: Find, Rapidly, OTUs with Galaxy Solution.
Frédéric Escudié,Lucas Auer,Maria Bernard,Mahendra Mariadassou,Laurent Cauquil,Katia Vidal,Sarah Maman,Guillermina Hernandez-Raquet,Sylvie Combes,Géraldine Pascal +9 more
TL;DR: This Galaxy‐supported pipeline, called FROGS, is designed to analyze large sets of amplicon sequences and produce abundance tables of Operational Taxonomic Units (OTUs) and their taxonomic affiliation to highlight databases conflicts and uncertainties.
Journal ArticleDOI
Uncovering latent structure in valued graphs: A variational approach
TL;DR: In this paper, a model-based strategy to uncover groups of nodes in valued graphs is presented, which can be used for a wide span of parametric random graphs models and allows to include covariates.
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Beneficial metabolic effects of selected probiotics on diet-induced obesity and insulin resistance in mice are associated with improvement of dysbiotic gut microbiota
Jeanne Alard,Véronique Lehrter,Moez Rhimi,Moez Rhimi,Irène Mangin,Véronique Peucelle,Anne-Laure Abraham,Anne-Laure Abraham,Mahendra Mariadassou,Emmanuelle Maguin,Emmanuelle Maguin,Anne-Judith Waligora-Dupriet,Bruno Pot,Isabelle Wolowczuk,Corinne Grangette +14 more
TL;DR: A multi-strain mixture was able to improve adiposity, insulin resistance and dyslipidemia through adipose tissue immune cell-remodelling, mainly affecting macrophages, and it was shown that the probiotic mixture favours the production of butyrate and propionate.
Journal ArticleDOI
Quantitative prediction of genome-wide resource allocation in bacteria
Anne Goelzer,Jan Muntel,Victor Chubukov,Matthieu Jules,Matthieu Jules,Eric Prestel,Eric Prestel,Rolf Nölker,Mahendra Mariadassou,Stéphane Aymerich,Stéphane Aymerich,Michael Hecker,Philippe Noirot,Philippe Noirot,Dörte Becher,Vincent Fromion +15 more
TL;DR: It is shown that the constraint-based modeling method Resource Balance Analysis (RBA), calibrated using genome-wide absolute protein quantification data, accurately predicts resource allocation in the model bacterium Bacillus subtilis for a wide range of growth conditions.
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Gut bacteria are critical for optimal muscle function: a potential link with glucose homeostasis.
Kevin Nay,Kevin Nay,Maxence Jollet,Bénédicte Goustard,Narjes Baati,Barbara Vernus,Maria Pontones,Luz Lefeuvre-Orfila,Claude Bendavid,Olivier Rué,Mahendra Mariadassou,Anne Bonnieu,Vincent Ollendorff,Patricia Lepage,Frédéric Derbré,Christelle Koechlin-Ramonatxo +15 more
TL;DR: The hypothesis that gut bacteria are required for host optimal skeletal muscle function is strongly supported, as several pertinent glucose metabolism markers paralleled the muscle endurance changes observed after ATB treatment and reseeding.