P
Philippe Noirot
Researcher at Institut national de la recherche agronomique
Publications - 46
Citations - 4716
Philippe Noirot is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Bacillus subtilis & DNA replication. The author has an hindex of 35, co-authored 45 publications receiving 4284 citations. Previous affiliations of Philippe Noirot include Public Health Research Institute & Harvard University.
Papers
More filters
Journal ArticleDOI
Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis
Pierre Nicolas,Ulrike Mäder,Etienne Dervyn,Tatiana Rochat,Aurélie Leduc,Nathalie Pigeonneau,Elena Bidnenko,Elodie Marchadier,Mark Hoebeke,Stéphane Aymerich,Dörte Becher,Paola Bisicchia,Eric Botella,Olivier Delumeau,Geoff Doherty,Emma L. Denham,Mark J. Fogg,Vincent Fromion,Anne Goelzer,Annette Hansen,Elisabeth Härtig,Colin R. Harwood,Georg Homuth,Hanne Østergaard Jarmer,Matthieu Jules,Edda Klipp,Ludovic Le Chat,François Lecointe,Peter J. Lewis,Wolfram Liebermeister,Anika March,Ruben A. T. Mars,Priyanka Nannapaneni,David Noone,Susanne Pohl,Bernd Rinn,Frank Rügheimer,Praveen K. Sappa,Franck Samson,Marc Schaffer,Benno Schwikowski,Leif Steil,Jörg Stülke,Thomas Wiegert,Kevin M. Devine,Anthony J. Wilkinson,Jan Maarten van Dijl,Michael Hecker,Uwe Völker,Philippe Bessières,Philippe Noirot +50 more
TL;DR: The transcriptomes of Bacillus subtilis exposed to a wide range of environmental and nutritional conditions that the organism might encounter in nature are reported, offering an initial understanding of why certain regulatory strategies may be favored during evolution of dynamic control systems.
Journal ArticleDOI
Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism
Joerg Martin Buescher,Wolfram Liebermeister,Matthieu Jules,Markus Uhr,Jan Muntel,Eric Botella,Bernd Hessling,Roelco J. Kleijn,Ludovic Le Chat,François Lecointe,Ulrike Mäder,Pierre Nicolas,Sjouke Piersma,Frank Rügheimer,Dörte Becher,Philippe Bessières,Elena Bidnenko,Emma L. Denham,Etienne Dervyn,Kevin M. Devine,Geoff Doherty,Samuel Drulhe,Liza Felicori,Mark J. Fogg,Anne Goelzer,Annette Hansen,Colin R. Harwood,Michael Hecker,Sebastian Hubner,Claus Hultschig,Hanne Østergaard Jarmer,Edda Klipp,Aurélie Leduc,Peter J. Lewis,F. Molina,Philippe Noirot,Sabine Peres,Nathalie Pigeonneau,Susanne Pohl,Simon Rasmussen,Bernd Rinn,Marc Schaffer,Julian Schnidder,Benno Schwikowski,Jan Maarten van Dijl,Patrick Veiga,Sean Walsh,Anthony J. Wilkinson,Jörg Stelling,Stéphane Aymerich,Uwe Sauer +50 more
TL;DR: The responses of a bacterium to changing nutritional conditions are explored and an initial understanding of why certain regulatory strategies may be favored during evolution of dynamic control systems is offered.
Journal ArticleDOI
A Key Presynaptic Role in Transformation for a Widespread Bacterial Protein: DprA Conveys Incoming ssDNA to RecA
Isabelle Mortier-Barrière,Marion Velten,Pauline Dupaigne,Nicolas Mirouze,Nicolas Mirouze,Olivier Piétrement,Stephen McGovern,Gwennaele Fichant,Bernard Martin,Philippe Noirot,Eric Le Cam,Patrice Polard,Jean-Pierre Claverys +12 more
TL;DR: It is proposed that DprA is a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation, and it is shown that while the Escherichia coli ssDNA-binding protein SSB limits access of RecA to ssDNA, DPRA lowers this barrier.
Journal ArticleDOI
Actin Homolog MreBH Governs Cell Morphogenesis by Localization of the Cell Wall Hydrolase LytE
Rut Carballido-López,Rut Carballido-López,Alex Formstone,Ying Li,S. Dusko Ehrlich,Philippe Noirot,Jeff Errington,Jeff Errington +7 more
TL;DR: It is proposed that controlled elongation of rod-shaped B. subtilis depends on the coordination of cell wall synthesis and hydrolysis in helical tracts defined by MreB proteins, and that physical interactions with intracellular actin bundles can influence the later localization pattern of extracellular effectors.
Journal ArticleDOI
An expanded view of bacterial DNA replication
Marie-Françoise Noirot-Gros,Etienne Dervyn,Ling Juan Wu,Peggy Mervelet,Jeffery Errington,S. Dusko Ehrlich,Philippe Noirot +6 more
TL;DR: A protein-interaction network centered on the replication machinery of Bacillus subtilis was generated by genome-wide two-hybrid screens and systematic specificity assays, providing insights on the relations of DNA replication with recombination and repair, membrane-bound protein complexes, and signaling pathways.