M
Makiko Nakahana
Researcher at Kobe University
Publications - 4
Citations - 39
Makiko Nakahana is an academic researcher from Kobe University. The author has contributed to research in topics: DNA damage & Microvesicles. The author has an hindex of 3, co-authored 4 publications receiving 15 citations.
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Exosome-mediated radiosensitizing effect on neighboring cancer cells via increase in intracellular levels of reactive oxygen species.
Ai Nakaoka,Makiko Nakahana,Sachiko Inubushi,Hiroaki Akasaka,Mohammed Salah,Yoshiko Fujita,Hikaru Kubota,Mennaallah Hassan,Ryo Nishikawa,Naritoshi Mukumoto,Takeaki Ishihara,Daisuke Miyawaki,Takashi Sasayama,Ryohei Sasaki +13 more
TL;DR: The role of exosomes in intercellular communication between cancer cells following radiation exposure is unclear as mentioned in this paper, however, the exact mechanism of the interaction between cells and neighboring cancer cells is unclear.
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Amelioration of Radiation Enteropathy by Dietary Supplementation With Reduced Coenzyme Q10.
Yasuyuki Shimizu,Naritoshi Mukumoto,Nelly Idrus,Hiroaki Akasaka,Sachiko Inubushi,Kenji Yoshida,Daisuke Miyawaki,Takeaki Ishihara,Yoshiaki Okamoto,Takahiro Yasuda,Makiko Nakahana,Ryohei Sasaki +11 more
TL;DR: Administration of rCoQ10 led to its accumulation in the intestine and induced radioprotective effects by inhibiting ROS-mediated apoptosis, thereby preserving intestinal structures, and indicated that r coenzyme Q10 supplementation effectively ameliorated radiation enteropathy.
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A Comparative Assessment of Mechanisms and Effectiveness of Radiosensitization by Titanium Peroxide and Gold Nanoparticles.
Mennaallah Hassan,Masao Nakayama,Masao Nakayama,Mohammed Salah,Mohammed Salah,Hiroaki Akasaka,Hikaru Kubota,Makiko Nakahana,Tatsuichiro Tagawa,Kenta Morita,Ai Nakaoka,Takeaki Ishihara,Daisuke Miyawaki,Kenji Yoshida,Yuya Nishimura,Chiaki Ogino,Ryohei Sasaki +16 more
TL;DR: A comparison of the types and amounts of ROS generated showed that hydrogen peroxide generation by PAA-TiOxNPs was the major factor that contributed to the nanoparticle radiosensitization.
Journal ArticleDOI
Elucidation of gastrointestinal dysfunction in response to irradiation using metabolomics.
Mohammed Salah,Mohammed Salah,Saki Osuga,Makiko Nakahana,Yasuhiro Irino,Masakazu Shinohara,Yasuyuki Shimizu,Naritoshi Mukumoto,Hiroaki Akasaka,Ai Nakaoka,Daisuke Miyawaki,Takeaki Ishihara,Kenji Yoshida,Yoshiaki Okamoto,Ryohei Sasaki +14 more
TL;DR: The findings raise the possibility that amino acid metabolism may be a potential target for the development of treatments to alleviate or mitigate the harmful effects of oxidative stress-related gastrointestinal toxicity due to radiation exposure.