M
Mallikarjuna Rao Pichika
Researcher at International Medical University
Publications - 76
Citations - 2464
Mallikarjuna Rao Pichika is an academic researcher from International Medical University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 17, co-authored 60 publications receiving 1649 citations.
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Journal ArticleDOI
Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol.
Swarnalatha Dugasani,Mallikarjuna Rao Pichika,Vishna Devi Nadarajah,Madhu Katyayani Balijepalli,Satyanarayana Tandra,Jayaveera Narsimha Korlakunta +5 more
TL;DR: 6-Shogaol has exhibited the most potent antioxidant and anti-inflammatory properties which can be attributed to the presence of alpha,beta-unsaturated ketone moiety, and this study justifies the use of dry ginger in traditional systems of medicine.
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Artificial intelligence in drug development: present status and future prospects
TL;DR: The major causes of attrition rates in new drug approvals are discussed, the possible ways that AI can improve the efficiency of the drug development process and collaboration of pharmaceutical industry giants with AI-powered drug discovery firms are discussed.
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An update on natural compounds in the remedy of diabetes mellitus: A systematic review.
Hira Choudhury,Manisha Pandey,Chua Kui Hua,Cheah Shi Mun,Jessmie Koh Jing,Lillian Kong,Liang Yee Ern,Nik Ahmad Ashraf,Soohg Wai Kit,Tan Sin Yee,Mallikarjuna Rao Pichika,Bapi Gorain,Prashant Kesharwani,Prashant Kesharwani +13 more
TL;DR: This review focuses on the herbal and natural remedies that play the role in the treatment or prevention of this morbid disorder – diabetes, including their underlying mechanisms for the blood glucose-lowering property and the herbal products already been marketed for the remedial action of diabetes.
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A comprehensive review on polyelectrolyte complexes
Venkata Srikanth Meka,Manprit K.G. Sing,Mallikarjuna Rao Pichika,Srinivasa R. Nali,Venkata Ramana Murthy Kolapalli,Prashant Kesharwani +5 more
TL;DR: A comprehensive review on PECs and their classification, theory and characterization, as well as a critical analysis of the current research are provided.
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Chalcones with electron-withdrawing and electron-donating substituents: anticancer activity against TRAIL resistant cancer cells, structure-activity relationship analysis and regulation of apoptotic proteins.
TL;DR: The chal cone 38 containing an amino (-NH2) group on ring A was the most potent and selective against cancer cells and the effects of the chalcone 38 on regulation of 43 apoptosis-related markers in HT-29 cells were determined.