M
Malte Braunschweig
Researcher at Rockefeller University
Publications - 4
Citations - 1296
Malte Braunschweig is an academic researcher from Rockefeller University. The author has contributed to research in topics: Viral load & Antibody. The author has an hindex of 4, co-authored 4 publications receiving 1071 citations. Previous affiliations of Malte Braunschweig include University of Freiburg & Howard Hughes Medical Institute.
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Journal ArticleDOI
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
Marina Caskey,Florian Klein,Julio C. C. Lorenzi,Michael S. Seaman,Anthony P. West,Noreen Buckley,Gisela Kremer,Lilian Nogueira,Malte Braunschweig,Johannes F. Scheid,Joshua A. Horwitz,Irina Shimeliovich,Sivan Ben-Avraham,Maggi Witmer-Pack,Martin Platten,Clara Lehmann,Leah A. Burke,Thomas Hawthorne,Robert J. Gorelick,Bruce D. Walker,Tibor Keler,Roy M. Gulick,Gerd Fätkenheuer,Sarah J. Schlesinger,Michel C. Nussenzweig +24 more
TL;DR: It is concluded that, as a single agent, 3BNC117 is safe and effective in reducing HIV-1 viraemia, and that immunotherapy should be explored as a new modality for HIV- 1 prevention, therapy and cure.
Journal ArticleDOI
HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption
Johannes F. Scheid,Johannes F. Scheid,Joshua A. Horwitz,Yotam Bar-On,Edward F. Kreider,Ching-Lan Lu,Julio C. C. Lorenzi,Anna Feldmann,Malte Braunschweig,Lilian Nogueira,Thiago Y. Oliveira,Irina Shimeliovich,Roshni Patel,Leah A. Burke,Yehuda Z. Cohen,Sonya Hadrigan,Allison Settler,Maggi Witmer-Pack,Anthony P. West,Boris Juelg,Tibor Keler,Thomas Hawthorne,Barry S. Zingman,Roy M. Gulick,Nico Pfeifer,Gerald H. Learn,Michael S. Seaman,Pamela J. Bjorkman,Florian Klein,Florian Klein,Florian Klein,Sarah J. Schlesinger,Bruce D. Walker,Bruce D. Walker,Beatrice H. Hahn,Michel C. Nussenzweig,Marina Caskey +36 more
TL;DR: It is concluded that administration of 3BNC117 exerts strong selective pressure on HIV-1 emerging from latent reservoirs during ATI in humans, suggesting failure to escape over a period of 9-19 weeks.
Journal ArticleDOI
HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1
Till Schoofs,Florian Klein,Florian Klein,Florian Klein,Malte Braunschweig,Malte Braunschweig,Edward F. Kreider,Anna Feldmann,Lilian Nogueira,Thiago Y. Oliveira,Julio C. C. Lorenzi,Erica H. Parrish,Gerald H. Learn,Anthony P. West,Pamela J. Bjorkman,Sarah J. Schlesinger,Michael S. Seaman,Julie Czartoski,M. Juliana McElrath,Nico Pfeifer,Beatrice H. Hahn,Marina Caskey,Michel C. Nussenzweig,Michel C. Nussenzweig +23 more
TL;DR: HIV-1 immunotherapy with a single injection of 3BNC117 affects host antibody responses in viremic individuals and enhances host humoral immunity to HIV-1, and neutralizing antibodies may be a promising therapy for HIV- 1 because of their potential to reduce the viral reservoir.
Journal ArticleDOI
Corrigendum: Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.
Marina Caskey,Florian Klein,Julio C. C. Lorenzi,Michael S. Seaman,Anthony P. West,Noreen Buckley,Gisela Kremer,Lilian Nogueira,Malte Braunschweig,Johannes F. Scheid,Joshua A. Horwitz,Irina Shimeliovich,Sivan Ben-Avraham,Maggi Witmer-Pack,Martin Platten,Clara Lehmann,Leah A. Burke,Thomas Hawthorne,Robert J. Gorelick,Bruce D. Walker,Tibor Keler,Roy M. Gulick,Gerd Fätkenheuer,Sarah J. Schlesinger,Michel C. Nussenzweig +24 more
TL;DR: This corrects the article to show that the method used to derive the H2O2 “spatially aggregating force” is based on a two-step process, not a single step, like in the previous version of this paper.