M
Manjunath Goolyam Basavaraj
Researcher at Children's Hospital of Philadelphia
Publications - 8
Citations - 198
Manjunath Goolyam Basavaraj is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Monocyte & Tissue factor. The author has an hindex of 6, co-authored 8 publications receiving 178 citations. Previous affiliations of Manjunath Goolyam Basavaraj include University of Tromsø & Indian Institute of Science.
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Journal Article
Role of CYP1B1, MYOC, OPTN, and OPTC genes in adult-onset primary open-angle glaucoma: predominance of CYP1B1 mutations in Indian patients.
Arun Kumar,Manjunath Goolyam Basavaraj,Santosh Gupta,Imteyaz Qamar,Abdullah Mahmood Ali,Vineeta Bajaj,T. Ramesh,D. Ravi Prakash,Jyoti S Shetty,Syril Dorairaj +9 more
TL;DR: It is shown that mutations in these genes are rare in Indian POAG patients, the first report to document the involvement of the CYP1B1, MYOC, and OPTN genes in the etiology of POAG in the same set of Indian patients.
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Differential ability of tissue factor antibody clones on detection of tissue factor in blood cells and microparticles.
Manjunath Goolyam Basavaraj,Jan Ole Olsen,Bjarne Østerud,John-Bjarne Hansen,John-Bjarne Hansen +4 more
TL;DR: The authors' results suggest non-specific binding by the CLB/TF-5 and VIC7 antibodies in a FCM test system and explain at least some of the reports on TF presence in blood cells, particularly TF associated with platelets and MPs.
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The role of TFPI in regulation of TF-induced thrombogenicity on the surface of human monocytes
Manjunath Goolyam Basavaraj,Franz Gruber,Mikhail A. Sovershaev,Hege I. Appelbom,Bjarne Østerud,Lars Christian Petersen,John-Bjarne Hansen +6 more
TL;DR: The results support the concept that surface TFPI is an important regulator of procoagulant reactivity of human monocytes.
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Monocyte count and procoagulant functions are associated with risk of venous thromboembolism: the Tromsø study.
Manjunath Goolyam Basavaraj,Sigrid Kufaas Brækkan,Sigrid Kufaas Brækkan,Ellen Brodin,Ellen Brodin,Bjarne Østerud,John-Bjarne Hansen,John-Bjarne Hansen +7 more
TL;DR: A randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease predicts increased blood loss and transfusion requirement after off-pump coronary artery bypass graft surgery.
Journal ArticleDOI
Circulating monocytes mirror the imbalance in TF and TFPI expression in carotid atherosclerotic plaques with lipid-rich and calcified morphology
Manjunath Goolyam Basavaraj,Mikhail A. Sovershaev,Mikhail A. Sovershaev,Elena M. Egorina,Elena M. Egorina,Franz Gruber,Vladimir Y. Bogdanov,John T. Fallon,Bjarne Østerud,Ellisiv B. Mathiesen,Ellisiv B. Mathiesen,John-Bjarne Hansen,John-Bjarne Hansen +12 more
TL;DR: Findings indicate that circulating monocytes of asymptomatic individuals with echolucent lipid-rich carotid atherosclerotic plaques express an imbalance between TF and TFPI expression cohering with changes found within advanced carotids obtained from symptomatic patients.