M
Mansi Srivastava
Researcher at Indiana University – Purdue University Indianapolis
Publications - 55
Citations - 5194
Mansi Srivastava is an academic researcher from Indiana University – Purdue University Indianapolis. The author has contributed to research in topics: Gene & Biology. The author has an hindex of 16, co-authored 40 publications receiving 4620 citations. Previous affiliations of Mansi Srivastava include Massachusetts Institute of Technology & Harvard University.
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Journal ArticleDOI
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
Nicholas H. Putnam,Mansi Srivastava,Uffe Hellsten,Bill Dirks,Jarrod Chapman,Asaf Salamov,Astrid Terry,Harris Shapiro,Erika Lindquist,Vladimir V. Kapitonov,Jerzy Jurka,Grigory Genikhovich,Igor V. Grigoriev,Susan Lucas,Robert Steele,John R. Finnerty,Ulrich Technau,Mark Q. Martindale,Daniel S. Rokhsar,Daniel S. Rokhsar +19 more
TL;DR: A comparative analysis of the draft genome of an emerging cnidarian model, the starlet sea anemone Nematostella vectensis, suggests that gene “inventions” along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor.
Journal ArticleDOI
The Amphimedon queenslandica genome and the evolution of animal complexity
Mansi Srivastava,Oleg Simakov,Oleg Simakov,Jarrod Chapman,Bryony Fahey,Marie Gauthier,Marie Gauthier,Therese Mitros,Gemma S. Richards,Gemma S. Richards,Cecilia Conaco,Michael Dacre,Uffe Hellsten,Claire Larroux,Claire Larroux,Nicholas H. Putnam,Mario Stanke,Maja Adamska,Maja Adamska,Aaron E. Darling,Sandie M. Degnan,Todd H. Oakley,David C. Plachetzki,Yufeng Zhai,Marcin Adamski,Marcin Adamski,Andrew D Calcino,Scott F. Cummins,David Goodstein,Christina Harris,Daniel J. Jackson,Daniel J. Jackson,Sally P. Leys,Shengqiang Q. Shu,Ben J. Woodcroft,Michel Vervoort,Kenneth S. Kosik,Gerard Manning,Bernard M. Degnan,Daniel S. Rokhsar,Daniel S. Rokhsar +40 more
TL;DR: In this paper, the authors present the draft genome sequence of Amphimedon queenslandica, a demosponge from the Great Barrier Reef, and show that it is remarkably similar to other animal genomes in content, structure and organization.
Journal ArticleDOI
The Trichoplax genome and the nature of placozoans
Mansi Srivastava,Emina Begovic,Emina Begovic,Jarrod Chapman,Nicholas H. Putnam,Nicholas H. Putnam,Uffe Hellsten,Takeshi Kawashima,Takeshi Kawashima,Alan Kuo,Therese Mitros,Asaf Salamov,Meredith L. Carpenter,Ana Y. Signorovitch,María Ángeles Moreno,Kai Kamm,Jane Grimwood,Jeremy Schmutz,Harris Shapiro,Igor V. Grigoriev,Leo W. Buss,Bernd Schierwater,Stephen L. Dellaporta,Daniel S. Rokhsar,Daniel S. Rokhsar +24 more
TL;DR: Despite the apparent cellular and organismal simplicity of Trichoplax, its genome encodes a rich array of transcription factor and signalling pathway genes that are typically associated with diverse cell types and developmental processes in eumetazoans, motivating further searches for cryptic cellular complexity and/or as yet unobserved life history stages.
Journal ArticleDOI
Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals
Andrew Grimson,Mansi Srivastava,Bryony Fahey,Ben J. Woodcroft,H. Rosaria Chiang,Nicole King,Bernard M. Degnan,Daniel S. Rokhsar,Daniel S. Rokhsar,David P. Bartel +9 more
TL;DR: This work identifies small RNAs from animal phyla that diverged before the emergence of the Bilateria, a close relative of the cnidarian Nematostella vectensis (starlet sea anemone), which possesses an extensive repertoire of miRNA genes, two classes of piRNAs and a complement of proteins specific to small-RNA biology comparable to that of humans.
Journal ArticleDOI
Anatomy and development of the nervous system of Nematostella vectensis, an anthozoan cnidarian.
TL;DR: Early neurons and stem cell populations identified with NvMsi, NvELAV, and NvGCM, indicate that neural differentiation occurs throughout the animal and initiates prior to the conclusion of gastrulation.