J
John R. Finnerty
Researcher at Boston University
Publications - 81
Citations - 8941
John R. Finnerty is an academic researcher from Boston University. The author has contributed to research in topics: Nematostella & Starlet sea anemone. The author has an hindex of 38, co-authored 79 publications receiving 8347 citations. Previous affiliations of John R. Finnerty include University of Kentucky & University of Chicago.
Papers
More filters
Journal ArticleDOI
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
Amy E. Pasquinelli,Brenda J. Reinhart,Frank J. Slack,Mark Q. Martindale,Mitzi I. Kuroda,Betsy Maller,David C. Hayward,Eldon E. Ball,Bernard M. Degnan,Peter Müller,Jürg Spring,Ashok Srinivasan,Mark C. Fishman,John R. Finnerty,Joseph C. Corbo,Michael P. Levine,Patrick S. Leahy,Eric H. Davidson,Gary Ruvkun +18 more
TL;DR: Two small RNAs regulate the timing of Caenorhabditis elegans development and may control late temporal transitions during development across animal phylogeny.
Journal ArticleDOI
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
Nicholas H. Putnam,Mansi Srivastava,Uffe Hellsten,Bill Dirks,Jarrod Chapman,Asaf Salamov,Astrid Terry,Harris Shapiro,Erika Lindquist,Vladimir V. Kapitonov,Jerzy Jurka,Grigory Genikhovich,Igor V. Grigoriev,Susan Lucas,Robert Steele,John R. Finnerty,Ulrich Technau,Mark Q. Martindale,Daniel S. Rokhsar,Daniel S. Rokhsar +19 more
TL;DR: A comparative analysis of the draft genome of an emerging cnidarian model, the starlet sea anemone Nematostella vectensis, suggests that gene “inventions” along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor.
Journal ArticleDOI
Origins of Bilateral Symmetry: Hox and Dpp Expression in a Sea Anemone
TL;DR: It is shown that Nematostella uses homologous genes to achieve bilateral symmetry: Multiple Hox genes are expressed in a staggered fashion along its primary body axis, and the transforming growth factor–β gene decapentaplegic is expressed in an asymmetric fashion about its secondary body axis.
Journal ArticleDOI
Investigating the origins of triploblasty: 'mesodermal' gene expression in a diploblastic animal, the sea anemone Nematostella vectensis (phylum, Cnidaria; class, Anthozoa).
TL;DR: The developmental expression of seven genes from Nematostella are studied, and the predominantly endodermal expression of these genes reinforces the hypothesis that the mesoderm and endoderm of triploblastic animals could be derived from the endoderman of a diploblastics ancestor.
Journal ArticleDOI
The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases.
John R. Finnerty,John R. Finnerty,Wang-Xia Wang,Wang-Xia Wang,Sébastien S. Hébert,Sébastien S. Hébert,Bernard R. Wilfred,Bernard R. Wilfred,Guogen Mao,Guogen Mao,Peter T. Nelson,Peter T. Nelson +11 more
TL;DR: The miR-15/107 group of microRNA genes is a fascinating topic of study for evolutionary biologists, miRNA biochemists, and clinically oriented translational researchers alike and the roles played by these miRNAs in human diseases are investigated.