M
Mara Roxana Rubinstein
Researcher at Columbia University
Publications - 7
Citations - 1821
Mara Roxana Rubinstein is an academic researcher from Columbia University. The author has contributed to research in topics: Fusobacterium nucleatum & Cancer. The author has an hindex of 4, co-authored 6 publications receiving 1207 citations. Previous affiliations of Mara Roxana Rubinstein include Case Western Reserve University.
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Journal ArticleDOI
Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin
TL;DR: A mechanism by which Fn can drive CRC is unveiled and FadA is identified as a potential diagnostic and therapeutic target for CRC.
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Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β-catenin modulator Annexin A1.
Mara Roxana Rubinstein,Jung Eun Baik,Stephen M. Lagana,Richard P Han,William J. Raab,Debashis Sahoo,Piero Dalerba,Timothy C. Wang,Yiping W. Han +8 more
TL;DR: A “two‐hit” model in colorectal carcinogenesis is proposed, with somatic mutation(s) serving as the first hit, and F. nucleatum as the second hit exacerbating cancer progression after benign cells become cancerous.
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Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation.
Elena Y. Senchenkova,Junaid Ansari,Felix Becker,Shantel Vital,Zaki Al-Yafeai,Erica M. Sparkenbaugh,Rafal Pawlinski,Karen Y. Stokes,Jennifer L. Carroll,Ana-Maria Dragoi,Chengxue Qin,Rebecca H. Ritchie,Hai Sun,Hugo H. Cuellar-Saenz,Mara Roxana Rubinstein,Yiping W. Han,A. Wayne Orr,Mauro Perretti,D. Neil Granger,Felicity N. E. Gavins +19 more
TL;DR: This research presents a novel probabilistic approach that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus as a source of infection for other animals.
Journal ArticleDOI
Analysis of 16S rRNA genes reveals reduced Fusobacterial community diversity when translocating from saliva to GI sites.
Miles Richardson,Jihui Ren,Mara Roxana Rubinstein,Jamila A Taylor,Richard A. Friedman,Bo Shen,Yiping W. Han +6 more
TL;DR: This study elucidates selective translocation of oral fusobacteria to the GI tract and identifies specific transmissible clones to facilitate risk assessment for developing Fusobacterium-implicated GI disorders.
Journal ArticleDOI
Omega-3 fatty acids suppress Fusobacterium nucleatum–induced placental inflammation originating from maternal endothelial cells
Jeewon Garcia-So,Xinwen Zhang,Xiaohua Yang,Mara Roxana Rubinstein,De Yu Mao,Jan Kitajewski,Kang Liu,Yiping W. Han +7 more
TL;DR: The mechanism by which microbial infections affect pregnancy is revealed and a prophylactic therapy to protect against intrauterine infections is identified to prevent placental inflammation.