Marc Desforges

TL;DR: A global portrait of some of the most prevalent or emerging human respiratory viruses that have been associated with possible pathogenic processes in CNS infection, with a special emphasis on human coronaviruses.

TL;DR: This work identifies processes that may govern the severity and nature of HCoV OC43 neuropathogenesis and will make possible the development of therapeutic strategies to prevent occurrences.

TL;DR: Host and viral factors that participate in the regulation of the possible pathogenic processes associated with CNS infection by human coronaviruses are presented and the intricate interplay between virus and host target cells is tried in order to characterize their role in the virus life cycle as well as in the capacity of the cell to respond to viral invasion.

TL;DR: In this case report, severe encephalitis with no established cause developed in a child with SCID and through deep sequencing, human coronavirus OC43 was identified in brain tissue.

TL;DR: It has been suggested that these recognized human respiratory pathogens could be associated with the triggering or the exacerbation of neurological diseases for which the etiology remains unknown or poorly understood.