M
Marcel Jonges
Researcher at University of Amsterdam
Publications - 43
Citations - 2319
Marcel Jonges is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Neuraminidase & Influenza A virus. The author has an hindex of 19, co-authored 33 publications receiving 2004 citations. Previous affiliations of Marcel Jonges include Center for Infectious Disease Research and Policy & Erasmus University Rotterdam.
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Journal ArticleDOI
Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation
Bart L. Haagmans,Said H.S. Al Dhahiry,Chantal B.E.M. Reusken,V. Stalin Raj,Monica Galiano,Richard M. Myers,Gert Jan Godeke,Marcel Jonges,Elmoubasher Farag,Ayman Diab,Hazem Ghobashy,Farhoud Alhajri,Mohamed H. Al-Thani,Salih A. Al-Marri,Hamad Eid Al Romaihi,Abdullatif Al Khal,Alison Bermingham,Albert D. M. E. Osterhaus,Mohd M. AlHajri,Marion Koopmans +19 more
TL;DR: This study provides virological confirmation of MERS-CoV in camels and suggests a recent outbreak affecting both human beings and camels.
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Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding
Salin Chutinimitkul,Sander Herfst,John Steel,Anice C. Lowen,Jianqiang Ye,Debby van Riel,Eefje J. A. Schrauwen,Theo M. Bestebroer,Björn F. Koel,David F. Burke,Kyle H. Sutherland-Cash,Chris S. Whittleston,Colin A. Russell,Colin A. Russell,David J. Wales,Derek J. Smith,Derek J. Smith,Derek J. Smith,Marcel Jonges,Adam Meijer,Marion Koopmans,Guus F. Rimmelzwaan,Thijs Kuiken,Albert D. M. E. Osterhaus,Adolfo García-Sastre,Daniel R. Perez,Ron A. M. Fouchier +26 more
TL;DR: Altered receptor specificity of the virus with D222G thus affected interaction with cells of the human lower respiratory tract, possibly explaining the observed association with enhanced disease in humans.
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Middle East respiratory syndrome coronavirus (MERS-CoV) RNA and neutralising antibodies in milk collected according to local customs from dromedary camels, Qatar, April 2014.
Chantal B.E.M. Reusken,Elmoubasher Farag,Marcel Jonges,Gert-Jan Godeke,Ahmed M. El-Sayed,Suzan D. Pas,V. S. Raj,Khaled A. Mohran,H A Moussa,Hazem Ghobashy,Farhoud Alhajri,A K Ibrahim,A K Ibrahim,Berend Jan Bosch,S K Pasha,Hamad Al-Romaihi,Mohammed Al-Thani,Salih A. Al-Marri,Mohd M. AlHajri,Bart L. Haagmans,Marion Koopmans +20 more
TL;DR: The presence of MERS-CoV RNA in milk of camels actively shedding the virus warrants measures to prevent putative food-borne transmission of the virus.
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Introduction of Virulence Markers in PB2 of Pandemic Swine-Origin Influenza Virus Does Not Result in Enhanced Virulence or Transmission
Sander Herfst,Salin Chutinimitkul,Jianqiang Ye,Emmie de Wit,Vincent J. Munster,Eefje J. A. Schrauwen,Theo M. Bestebroer,Marcel Jonges,Adam Meijer,Marion Koopmans,Guus F. Rimmelzwaan,Albert D. M. E. Osterhaus,Daniel R. Perez,Ron A. M. Fouchier +13 more
TL;DR: It is concluded that surveillance studies aimed at detecting S-OIVs with increased virulence or transmission should not rely solely on virulence markers identified in the past but should include detailed characterization of virus phenotypes, guided by genetic signatures of viruses detected in severe cases of disease in humans.
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Prolonged Influenza Virus Infection during Lymphocytopenia and Frequent Detection of Drug-Resistant Viruses
TL;DR: Clinical improvement in influenza lower respiratory tract infection is observed during oseltamivir treatment, but complete viral clearance is dependent on lymphocyte reconstitution, irrespective of receipt of antiviral medication.