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Marcelo Kern

Researcher at University of York

Publications -  6
Citations -  568

Marcelo Kern is an academic researcher from University of York. The author has contributed to research in topics: Cellulase & Opium Poppy. The author has an hindex of 5, co-authored 6 publications receiving 492 citations.

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A Papaver somniferum 10-Gene Cluster for Synthesis of the Anticancer Alkaloid Noscapine

TL;DR: In this paper, the exclusive expression of 10 genes encoding five distinct enzyme classes in a high noscapine-producing poppy variety, HN1, was found to be tightly linked in HN 1 and bacterial artificial chromosome sequencing confirmed that they exist as a complex gene cluster for plant alkaloids.
Journal ArticleDOI

Morphinan biosynthesis in opium poppy requires a P450-oxidoreductase fusion protein.

TL;DR: The identification of an unusual protein that contains both cytochrome P-450 and oxidoreductase modules may enable microbial-based morphinan production and enable alternate routes for morphine biosynthesis that are less dependent on poppy cultivation.
Journal ArticleDOI

Characterization of the cellulolytic secretome of Trichoderma harzianum during growth on sugarcane bagasse and analysis of the activity boosting effects of swollenin.

TL;DR: Despite lacking detectable glycoside activity, the addition of swollenin of T. harzianum increased by two‐fold the hydrolysis efficiency of a commercial cellulase cocktail, and the findings are of interest in enriching enzyme cocktail with this important accessory protein which takes part in the cellulose amorphogenesis.