M
Marco Fizzotti
Researcher at University of Perugia
Publications - 32
Citations - 2325
Marco Fizzotti is an academic researcher from University of Perugia. The author has contributed to research in topics: Lymphoma & Germinal center. The author has an hindex of 17, co-authored 30 publications receiving 2259 citations.
Papers
More filters
Journal ArticleDOI
ALK+ Lymphoma: Clinico-Pathological Findings and Outcome
Brunangelo Falini,Stefano Pileri,Pier Luigi Zinzani,Antonino Carbone,Vittorina Zagonel,Chris De Wolf-Peeters,Gregor Verhoef,Fabio Menestrina,Giuseppe Todeschini,Marco Paulli,Mario Lazzarino,Roberta Giardini,Antonella Aiello,Hans Dieter Foss,Iguacyra Araujo,Marco Fizzotti,Pier Giuseppe Pelicci,L. Flenghi,Massimo F. Martelli,Antonella Santucci +19 more
TL;DR: Multivariate analysis identified ALK expression and the International Prognostic Index as independent variables that were able to predict survival among T/null primary, systemic anaplastic large-cell lymphoma.
Journal ArticleDOI
A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells
Brunangelo Falini,Marco Fizzotti,Alessandra Pucciarini,Barbara Bigerna,Teresa Marafioti,Marcello Gambacorta,Roberta Pacini,Cristina Alunni,Laura Natali-Tanci,Barbara Ugolini,Carla Sebastiani,Giorgio Cattoretti,Stefano Pileri,Riccardo Dalla-Favera,Harald Stein +14 more
TL;DR: The results suggest that MUM1 is involved in the late stages of B-cell differentiation and in T-cell activation and is deregulated in DLCL-B.
Journal ArticleDOI
ALK Expression Defines a Distinct Group of T/Null Lymphomas (“ALK Lymphomas”) with a Wide Morphological Spectrum
Brunangelo Falini,Barbara Bigerna,Marco Fizzotti,Karen Pulford,Stefano Pileri,Georges Delsol,Antonino Carbone,Marco Paulli,Umberto Magrini,Umberto Magrini,Fabio Menestrina,Roberte Giardini,Silvana Pilotti,A Mezzelani,Barbara Ugolini,Monia Billi,Alessandra Pucciarini,Roberta Pacini,Pier Giuseppe Pelicci,L. Flenghi +19 more
TL;DR: It is suggested that the neoplastic lesion (the NPM-ALK gene) must be present both in the large anaplastic and small tumor cells, and that ALK-positive lymphomas lie on a spectrum, their position being defined by the ratio of small to large neoplastics cells.
Journal ArticleDOI
Lymphomas expressing ALK fusion protein(s) other than NPM-ALK.
Brunangelo Falini,Karen Pulford,Alessandra Pucciarini,Antonino Carbone,Chris De Wolf-Peeters,Jacqueline Cordell,Marco Fizzotti,Antonella Santucci,Pier Giuseppe Pelicci,Stefano Pileri,Elias Campo,German Ott,Georges Delsol,David Y. Mason +13 more
TL;DR: The results suggest that lymphomas carrying variants of the NPM-ALK fusion protein can be detected by immunostaining for ALK and NPM and also that they can be grouped with classical t(2;5)-positive tumors as a single entity that shows a better prognosis than ALK-negative anaplastic large-cell lymphomas.
Journal ArticleDOI
Distinctive expression pattern of the BCL-6 protein in nodular lymphocyte predominance Hodgkin's disease
Brunangelo Falini,Barbara Bigerna,Laura Pasqualucci,Marco Fizzotti,M F Martelli,Stefano Pileri,A Pinto,A Carbone,S. Venturi,Roberta Pacini,Giorgio Cattoretti,E. Pescarmona,F Lo Coco,Pier Giuseppe Pelicci,I Anagnastopoulos,R. Dalla-Favera,L. Flenghi +16 more
TL;DR: The findings suggest that BCL-6 may play a role in regulating differentiation of normal germinal center B cells and that its deregulated expression caused by rearrangements may contribute to lymphomagenesis.