M
Marcus P. S. Dekens
Researcher at Research Institute of Molecular Pathology
Publications - 17
Citations - 1326
Marcus P. S. Dekens is an academic researcher from Research Institute of Molecular Pathology. The author has contributed to research in topics: Zebrafish & Circadian rhythm. The author has an hindex of 12, co-authored 16 publications receiving 1211 citations. Previous affiliations of Marcus P. S. Dekens include University College London & Max Planck Society.
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Journal ArticleDOI
A radiation hybrid map of the zebrafish genome
Robert Geisler,Gerd-Jörg Rauch,Herwig Baier,F. van Bebber,L Bross,Marcus P. S. Dekens,K Finger,C. Fricke,Michael A. Gates,Horst Geiger,Silke Geiger-Rudolph,Darren Gilmour,S Glaser,L Gnügge,H Habeck,K Hingst,Scott A. Holley,J Keenan,Annette Kirn,Holger Knaut,Deval A. Lashkari,Florian Maderspacher,U Martyn,Stephan C.F. Neuhauss,Carl J. Neumann,Teresa Nicolson,Francisco Pelegri,Russell S. Ray,Jens M. Rick,Henry Roehl,T Roeser,Heike E. Schauerte,Alexander F. Schier,U Schönberger,Helia B. Schonthaler,Stefan Schulte-Merker,C Seydler,William S. Talbot,Christian Weiler,Christiane Nüsslein-Volhard,Pascal Haffter +40 more
TL;DR: A radiation hybrid (RH) map of the zebrafish genome is created, based on somatic cell hybrid lines produced by fusion of lethally irradiated cells of the species of interest with a rodent cell line to facilitate the mapping of candidate genes and to increase the density of markers available for positional cloning.
Journal ArticleDOI
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes
Alan J. Davidson,Patricia Ernst,Yuan Wang,Marcus P. S. Dekens,Paul D. Kingsley,James Palis,Stanley J. Korsmeyer,George Q. Daley,Leonard I. Zon +8 more
TL;DR: It is demonstrated that caudal-related gene cdx4 regulates hox genes and is necessary for the specification of haematopoietic cell fate during vertebrate embryogenesis.
Journal ArticleDOI
Light Regulates the Cell Cycle in Zebrafish
Marcus P. S. Dekens,Cristina Santoriello,Daniela Vallone,Gabriele Grassi,David Whitmore,Nicholas S. Foulkes +5 more
TL;DR: It is demonstrated that light plays a key role in cell cycle regulation in the zebrafish, and the cell-autonomous circadian clock is implicate in the regulation of the vertebrate cell cycle by light.
Journal ArticleDOI
Autonomous onset of the circadian clock in the zebrafish embryo
TL;DR: A default mechanism in the embryo is demonstrated that initiates the autonomous onset of the circadian clock and Transient expression of dominant‐negative ΔCLOCK blocks period1 transcription, thus showing that endogenous CLOCK is essential for the transcriptional regulation of period1 in the embryos.
Journal ArticleDOI
The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote.
TL;DR: It is proposed that in mitotic spindle assembly chromosome-dependent microtubule nucleation is essential for the coupling of nuclear and cell division.