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William S. Talbot
Researcher at Stanford University
Publications - 105
Citations - 14782
William S. Talbot is an academic researcher from Stanford University. The author has contributed to research in topics: Zebrafish & Myelin. The author has an hindex of 59, co-authored 97 publications receiving 13888 citations. Previous affiliations of William S. Talbot include New York University & University of Washington.
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The drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily
Michael R. Koelle,William S. Talbot,William A. Segraves,Michael T. Bender,Peter Cherbas,David S. Hogness +5 more
TL;DR: The steroid hormone ecdysone triggers coordinate changes in Drosophila tissue development that result in metamorphosis and a gene, EcR, is isolated and characterized for a new steroid receptor homolog and it is shown that it encodes an ecDysone receptor.
Journal ArticleDOI
Vertebrate genome evolution and the zebrafish gene map.
John H. Postlethwait,Yi-Lin Yan,Michael A. Gates,Sally Horne,Angel Amores,Alison Brownlie,Adriana Donovan,Elizabeth S. Egan,Allan Force,Zhiyuan Gong,Carole Goutel,Andreas Fritz,Robert N. Kelsh,Ela W. Knapik,Eric C. Liao,Barry H. Paw,David Ransom,Amy Singer,Margaret Thomson,Tariq S. Abduljabbar,Pamela C. Yelick,D. R. Beier,Jean-Stéphane Joly,Dan Larhammar,Frédéric M. Rosa,Monte Westerfield,Leonard I. Zon,Steve L. Johnson,William S. Talbot +28 more
TL;DR: This zebrafish gene map will facilitate molecular identification of mutated zebra-fish genes, which can suggest functions for human genes known only by sequence, and is likely that two polyploidization events occurred prior to the divergence of fish and mammal lineages.
Journal ArticleDOI
The EGF-CFC Protein One-Eyed Pinhead Is Essential for Nodal Signaling
Kira Gritsman,Jiaojiao Zhang,Simon Cheng,Elizabeth Heckscher,William S. Talbot,Alexander F. Schier +5 more
TL;DR: It is reported that embryos lacking both maternal and zygotic Oep activity are defective in germ layer formation, organizer development, and the positioning of the anterior-posterior axis.
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Zebrafish Comparative Genomics and the Origins of Vertebrate Chromosomes
John H. Postlethwait,Ian G. Woods,Phuong Ngo-Hazelett,Yi-Lin Yan,Peter D. Kelly,Felicia Chu,Hui Huang,Alicia Hill-Force,William S. Talbot +8 more
TL;DR: Comparative analysis suggests that an excess of chromosome fissions in the tetrapod lineage may account for chromosome numbers and provides histories for several human chromosomes.
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Zebrafish organizer development and germ-layer formation require nodal-related signals
Benjamin Feldman,Michael A. Gates,Elizabeth S. Egan,Scott T. Dougan,Gabriela Rennebeck,Howard I. Sirotkin,Alexander F. Schier,William S. Talbot +7 more
TL;DR: It is reported that the zebrafish squint (sqt) and cyclops (cyc) genes have essential, although partly redundant, functions in organizer development and also in the formation of mesoderm and endoderm.