M
Margaret C. Neville
Researcher at University of Colorado Denver
Publications - 126
Citations - 9493
Margaret C. Neville is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Lactation & Mammary gland. The author has an hindex of 48, co-authored 124 publications receiving 8863 citations. Previous affiliations of Margaret C. Neville include Anschutz Medical Campus & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Hormonal regulation of mammary differentiation and milk secretion.
TL;DR: Because a full-term pregnancy in early life is associated with a reduction in breast carcinogenesis, an understanding of the mechanisms by which these hormones bring about secretory differentiation may offer clues to the prevention of breast cancer.
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Studies in human lactation: milk volumes in lactating women during the onset of lactation and full lactation.
Margaret C. Neville,Ronald P. Keller,Joy M. Seacat,V Lutes,Marianne R. Neifert,Clare E. Casey,Jonathan C. Allen,Philip G. Archer +7 more
TL;DR: There was a characteristic milk volume for each mother-infant pair that was significantly related to infant weight at 1 mo, suggesting that infant and/or maternal factors coming into play during the first month of life are strong determinants of subsequent milk transfer to the infant.
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Tight junction regulation in the mammary gland.
TL;DR: The tight junction state appears to be closely linked to milk secretion, and anincrease in tight junction permeability is accompanied by decrease in the milk secretion rate, and conversely, a decrease in tight junctions permeability are accompanied by an increase in the Milk secretion rate.
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Mammary physiology and milk secretion.
TL;DR: Current understanding of the normal solute transport and secretory processes involved in milk production are reviewed, and potential regulatory mechanisms are discussed.
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Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis!
TL;DR: In this article, the sterol regulatory element binding protein (SREBP) family of transcription factors is recognized as regulating fatty acid and cholesterol biosynthesis, in a manner that responds to diet, and the serine/threonine protein kinase Akt influences this process.