M
Maria A. Rocca
Researcher at Vita-Salute San Raffaele University
Publications - 647
Citations - 29881
Maria A. Rocca is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Multiple sclerosis & Magnetic resonance imaging. The author has an hindex of 83, co-authored 556 publications receiving 25283 citations. Previous affiliations of Maria A. Rocca include University at Buffalo & Katholieke Universiteit Leuven.
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Journal ArticleDOI
Multiple sclerosis: Monitoring long-term treatments in multiple sclerosis
Massimo Filippi,Maria A. Rocca +1 more
TL;DR: Patients with relapsing-remitting multiple sclerosis have been shown to benefit from disease-modifying treatments over prolonged periods, and more focus should now be placed on monitoring the long-term evolution of this disease, alongside the patients' response and adherence to such treatments.
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Demyelination and cortical reorganization: functional MRI data from a case of subacute combined degeneration.
Massimo Filippi,Maria A. Rocca,Paolo Rossi,Andrea Falini,Letizia Leocani,Vittorio Martinelli,Giancarlo Comi +6 more
TL;DR: This multiparametric magnetic resonance study of a patient with an early diagnosis of subacute combined degeneration suggests that demyelination alone does not necessarily induce adaptive functional changes of the cerebral cortex.
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Effects on cognition of DMTs in multiple sclerosis: moving beyond the prevention of inflammatory activity.
TL;DR: In this paper, a review of recent findings derived from randomized controlled trials (RCTs), observational studies and meta-analyses that have been published in the last 3 years and that included the effects of DMTs on cognitive performances among their outcomes is presented.
Journal ArticleDOI
The association between cognition and motor performance is beyond structural damage in relapsing–remitting multiple sclerosis
Damiano Mistri,Laura Cacciaguerra,Loredana Storelli,Alessandro Masoni,Claudio Cordani,Maria A. Rocca,Massimo Filippi +6 more
TL;DR: In RRMS patients, deficit in information processing speed and executive function may contribute to hand motor dysfunction beyond the effect of structural disease-related burden, supporting the integration of motor and cognitive assessment in clinical settings.
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Siponimod for Cognition in Secondary Progressive Multiple Sclerosis: Thinking Through the Evidence
TL;DR: A recent meta-analysis assessing the benefits of DMTs for cognition in relapsing-remitting MS found a small improvement across 44 studies included as mentioned in this paper, however, there has been very little work evaluating the benefits for DMT-based treatments in progressive MS.