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Maria A. Rocca

Researcher at Vita-Salute San Raffaele University

Publications -  647
Citations -  29881

Maria A. Rocca is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Multiple sclerosis & Magnetic resonance imaging. The author has an hindex of 83, co-authored 556 publications receiving 25283 citations. Previous affiliations of Maria A. Rocca include University at Buffalo & Katholieke Universiteit Leuven.

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Multiple sclerosis: Monitoring long-term treatments in multiple sclerosis

TL;DR: Patients with relapsing-remitting multiple sclerosis have been shown to benefit from disease-modifying treatments over prolonged periods, and more focus should now be placed on monitoring the long-term evolution of this disease, alongside the patients' response and adherence to such treatments.
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Demyelination and cortical reorganization: functional MRI data from a case of subacute combined degeneration.

TL;DR: This multiparametric magnetic resonance study of a patient with an early diagnosis of subacute combined degeneration suggests that demyelination alone does not necessarily induce adaptive functional changes of the cerebral cortex.
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Effects on cognition of DMTs in multiple sclerosis: moving beyond the prevention of inflammatory activity.

TL;DR: In this paper, a review of recent findings derived from randomized controlled trials (RCTs), observational studies and meta-analyses that have been published in the last 3 years and that included the effects of DMTs on cognitive performances among their outcomes is presented.
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The association between cognition and motor performance is beyond structural damage in relapsing–remitting multiple sclerosis

TL;DR: In RRMS patients, deficit in information processing speed and executive function may contribute to hand motor dysfunction beyond the effect of structural disease-related burden, supporting the integration of motor and cognitive assessment in clinical settings.
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Siponimod for Cognition in Secondary Progressive Multiple Sclerosis: Thinking Through the Evidence

TL;DR: A recent meta-analysis assessing the benefits of DMTs for cognition in relapsing-remitting MS found a small improvement across 44 studies included as mentioned in this paper, however, there has been very little work evaluating the benefits for DMT-based treatments in progressive MS.